AI Article Synopsis
- The study examined the use of intravenous amiodarone (AMD) for treating post-operative atrial fibrillation (POAF) in cardiac surgery patients.
- After an initial rapid dose, AMD was delivered through a tailored drip over a period of 24 hours before switching to oral administration.
- Out of 25 patients, 72% experienced successful defibrillation with this treatment, suggesting that amiodarone may be a viable option for managing POAF.
Article Abstract
We investigated the effect of amiodarone (AMD) administered intravenously for the treatment of post-operative atrial fibrillation( POAF) after cardiac surgery. After rapid administration of 150 mg for 10 minutes, AMD was administered in 1.0 mg per minute for 6 hours followed by 0.5 mg per minute for 18 hours. AMD was then administered orally 200 mg per day for 1 or 2 weeks. Twenty-five cases were enrolled from January 2010 to June 2013. In 18 cases(72%), the patients were successfully defibrillated by this protocol. In the other 7 cases, the patients required electrical defibrillation, but in 1 patient developed chronic atrial fibrillation. It was thought that AMD could be a choice for POAF.
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