Background: The adult population of Glasgow has worse health than in the rest of Scotland, only partially explained by deprivation. Little is known about the health of young Glaswegians.
Methods: The 2010 Health Behaviour in School-aged Children survey data were analysed using multilevel modelling to compare outcomes in Glasgow relative to the rest of Scotland.
Results: Glasgow adolescents had similar or better self-reported health on some measures--e.g. adjusting for age and sex, OR for 'very happy' was 0.93 (95% CI = (0.75, 1.14))--and the beta coefficient for positive GHQ-12 was 2.79 (0.72, 4.85) compared with the rest of Scotland. However, many health aspects were worse in Glasgow especially for eating and sedentary behaviour, subjective health and aggression, e.g. the OR for 'daily consumption of vegetables' was 0.59 (0.46, 0.77), of reporting 'excellent health' was 0.66 (0.50, 0.87); headaches was 1.40 (1.09, 1.80); however drinking alcohol in the past week was lower (OR 0.71 (0.50, 0.99)) and smoking, similar. Adjustment for family affluence and school type marginally attenuated the association with Glasgow.
Conclusions: The worse health experienced by Glasgow adults is only partially seen among young people in Glasgow; however, these are seen at the youngest ages in the study.
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http://dx.doi.org/10.1093/pubmed/fdu035 | DOI Listing |
Stem Cell Res Ther
December 2024
National Colorectal Disease CenterNanjing Hospital of Chinese Medicine, Affiliated to Nanjing University of Chinese Medicine, Nanjing, 210022, Jiangsu, People's Republic of China.
Background: Complex perianal fistulas, challenging to treat and prone to recurrence, often require surgical intervention that may cause fecal incontinence and lower quality of life due to large surgical wounds and potential sphincter damage. Human umbilical cord-derived MSCs (hUC-MSCs) and their exosomes (hUCMSCs-Exo) may promote wound healing.
Methods: This study assessed the efficacy, mechanisms, and safety of these exosomes in treating complex perianal fistulas in SD rats.
Cardiovasc Diabetol
December 2024
Institute of Physiology, iCBR, Faculty of Medicine, University of Coimbra, Subunit 1, polo 3, Azinhaga de Santa Comba, Celas, 3000-548, Coimbra, Portugal.
Perivascular adipose tissue (PVAT) is a dynamic tissue that affects vascular function and cardiovascular health. The connection between PVAT, the immune system, obesity, and vascular disease is complex and plays a pivotal role in the pathogenesis of vascular diseases such as atherosclerosis, hypertension, and vascular inflammation. In cardiometabolic diseases, PVAT becomes a significant source of proflammatory adipokines, leading to increased infiltration of immune cells, in cardiometabolic diseases, PVAT becomes a significant source of proinflammatory adipokines, leading to increased infiltration of immune cells, promoting vascular smooth muscle cell proliferation and migrationpromoting vascular smooth muscle cell proliferation and migration.
View Article and Find Full Text PDFJ Med Case Rep
December 2024
Division of Infectious Diseases, Denver Health Medical Center, Denver, CO, USA.
Background: Leprosy (Hansen's disease) is an infectious disease most common in resource-limited countries caused by the acid-fast bacilli Mycobacterium leprae and Mycobacterium lepromatosis that frequently affects the skin and peripheral nerves. Prompt diagnosis and treatment with multidrug therapy is crucial to reduce disease transmission and sequelae, which include nerve function impairment, ocular injury, and stigmatizing physical deformities. Traditional treatment of multibacillary leprosy consists of 12-24 months of multidrug therapy with dapsone, rifampin, and clofazimine.
View Article and Find Full Text PDFNPJ Prim Care Respir Med
December 2024
ResMed Science Center, San Diego, CA, USA.
Digital health platforms for asthma self-management have demonstrated promise in improving clinical and quality of life outcomes. However, few studies have examined such an approach in a real-world, fully remote setting. As such, we evaluated the benefit of an evidence-based digital self-management platform for asthma-both on its own and when integrated into an established virtual clinical service.
View Article and Find Full Text PDFBMC Vet Res
December 2024
Department of Zoology, Faculty of Science, Benha University, Benha, 13518, Egypt.
Introduction: Heavy metal pollution threatens the biodiversity and ecological equilibrium of the Nile River. This study investigates the impact of heavy metal pollution on aquatic animals such as Nile tilapia (Oreochromis niloticus) in the Damietta branch of the River Nile and El-Rayah El-Tawfeeky canal in Benha City in Egypt.
Methods: Fish and water samples were collected from the Damietta branch and El-Rayah El-Tawfeeky during the fall of 2022.
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