Background: Chronic urticaria is characterized by swelling and itchy hives presenting remissions and exacerbations, for six weeks or more, which may or may not be accompanied by angioedema. Helicobacter pylori infection has been associated with various diseases among them chronic urticaria.
Objective: To determine the association between H. pylori infection and allergic and non-allergic chronic urticaria.
Material And Method: We conducted a retrospective, observational and cross-sectional study which included 82 patients of both sexes with a diagnosis of chronic urticaria, aged between 2 and 75 years. Total serum IgE and IgG anti-H. pylori were measured in all participants. Statistical analysis was performed using the chi-squared test with 0.05 significance.
Results: A total of 82 patients, 33 males and 49 females, with a mean age of 36.9 years were studied. H. pylori seropositivity was in 65.2% of allergic patients and 34.8% of non-allergic patients (p = 0.148).
Conclusions: We found no association between chronic allergic urticaria and H. pylori infection.
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mSystems
January 2025
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