AI Article Synopsis
- Behçet's disease is an autoimmune condition characterized by systemic vasculitis, which can occur after infections and has been linked to HIV.
- During chronic HIV infection, new cases of Behçet's disease may develop, and symptoms can improve with antiretroviral therapy.
- A patient with signs of systemic vasculitis, including skin and mucous membrane ulcerations, was diagnosed with Behçet's disease during acute HIV infection, suggesting a potential connection between HIV, immune activation, and the onset of autoimmune conditions.
Article Abstract
Behçet's disease is an autoimmune systemic vasculitis that can occur after exposure to infectious agents. Behçet's disease also has been associated with HIV infection, including de novo development of this condition during chronic HIV infection and resolution of Behçet's disease symptoms following initiation of antiretroviral therapy. We describe a patient who presented with systemic vasculitis with skin and mucous membrane ulcerations in the setting of acute HIV infection, who was eventually diagnosed with Behçet's disease, demonstrating a possible link between acute HIV infection, immune activation and development of autoimmunity.
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| http://dx.doi.org/10.1177/0956462414539667 | DOI Listing |
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