Identifying and characterizing clonal diversity are important when analysing fecal flora. We evaluated random amplified polymorphic DNA (RAPD) PCR, applied for selection of Escherichia coli isolates, by whole genome sequencing. RAPD was fast, and reproducible as screening method for selection of distinct E. coli clones in fecal swabs.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4166437PMC
http://dx.doi.org/10.1016/j.mimet.2014.05.018DOI Listing

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