Identifying and characterizing clonal diversity are important when analysing fecal flora. We evaluated random amplified polymorphic DNA (RAPD) PCR, applied for selection of Escherichia coli isolates, by whole genome sequencing. RAPD was fast, and reproducible as screening method for selection of distinct E. coli clones in fecal swabs.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4166437 | PMC |
http://dx.doi.org/10.1016/j.mimet.2014.05.018 | DOI Listing |
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