Peptide-catalyzed kinetic resolution of planar-chiral metallocenes. | LitMetric

A PHP Error was encountered

Severity: Warning

Message: file_get_contents(https://...@gmail.com&api_key=61f08fa0b96a73de8c900d749fcb997acc09): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests

Filename: helpers/my_audit_helper.php

Line Number: 143

Backtrace:

File: /var/www/html/application/helpers/my_audit_helper.php
Line: 143
Function: file_get_contents

File: /var/www/html/application/helpers/my_audit_helper.php
Line: 209
Function: simplexml_load_file_from_url

File: /var/www/html/application/helpers/my_audit_helper.php
Line: 3098
Function: getPubMedXML

File: /var/www/html/application/controllers/Detail.php
Line: 574
Function: pubMedSearch_Global

File: /var/www/html/application/controllers/Detail.php
Line: 488
Function: pubMedGetRelatedKeyword

File: /var/www/html/index.php
Line: 316
Function: require_once

A PHP Error was encountered

Severity: Warning

Message: Attempt to read property "Count" on bool

Filename: helpers/my_audit_helper.php

Line Number: 3100

Backtrace:

File: /var/www/html/application/helpers/my_audit_helper.php
Line: 3100
Function: _error_handler

File: /var/www/html/application/controllers/Detail.php
Line: 574
Function: pubMedSearch_Global

File: /var/www/html/application/controllers/Detail.php
Line: 488
Function: pubMedGetRelatedKeyword

File: /var/www/html/index.php
Line: 316
Function: require_once

Peptide-catalyzed kinetic resolution of planar-chiral metallocenes. | LitMetric

Peptide-catalyzed kinetic resolution of planar-chiral metallocenes.

Midori Akiyama Kengo Akagawa Hidetake Seino Kazuaki Kudo

Chem Commun (Camb)

Institute of Industrial Science, University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo 153-8505, Japan.

Published: July 2014

Kinetic resolution of racemic planar-chiral metallocenes was achieved using a nucleophile in the conjugate addition to the enal portion of the substrates.
Low-molecular-weight organocatalysts did not show any enantiomeric discrimination in the process.
A specially designed resin-supported peptide was able to catalyze the reaction with high selectivity.

Kinetic resolution of racemic planar-chiral metallocenes was performed through the conjugate addition of a nucleophile to the enal part of substrates. While no enantiomeric discrimination was found with low-molecular-weight organocatalysts, a properly designed resin-supported peptide catalyzed the reaction in a highly selective manner.

Download full-text PDF	Source
http://dx.doi.org/10.1039/c4cc03266g	DOI Listing

Publication Analysis

Top Keywords

kinetic resolution

8

planar-chiral metallocenes

8

peptide-catalyzed kinetic

4

resolution planar-chiral

4

metallocenes kinetic

4

resolution racemic

4

racemic planar-chiral

4

metallocenes performed

4

performed conjugate

4

conjugate addition

4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!

A PHP Error was encountered

Severity: Notice

Message: fwrite(): Write of 34 bytes failed with errno=28 No space left on device

Filename: drivers/Session_files_driver.php

Line Number: 272

Backtrace:

A PHP Error was encountered

Severity: Warning

Message: session_write_close(): Failed to write session data using user defined save handler. (session.save_path: /var/lib/php/sessions)

Filename: Unknown

Line Number: 0

Backtrace: