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The authors present the case of a 5-year-old boy who developed a unilateral internuclear ophthalmoplegia (INO) following mild head trauma with supporting magnetic resonance imaging (MRI) findings of damage to the medial longitudinal fasciculus. At 2 months of follow-up, the patient had resolution of diplopia and only minimal residual nystagmus. Although rare in the children, INO can develop following head trauma.

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Wall-Eyed Internuclear Ophthalmoplegia: History and Hypothesis.

Can J Neurol Sci

November 2024

Neuro-Ophthalmology Section, Division of Neurology, Departments of Medicine, Ophthalmology and Vision Sciences, University Health Network, University of Toronto, Toronto, ON, Canada.

Background: Most patients with internuclear ophthalmoplegia (INO) are orthotropic, although a subset is exotropic. When INO is bilateral, this is termed wall-eyed bilateral internuclear ophthalmoplegia (WEBINO). In 1979, Sharpe described his "first case" of wall-eyed monocular internuclear ophthalmoplegia (WEMINO) as "a unique clinical syndrome" characterized by unilateral INO and ipsilateral exotropia.

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Article Synopsis
  • Idiopathic Intracranial Hypertension (IIH) involves increased intracranial pressure with unknown origins, leading to symptoms like headaches, vision problems, and sometimes unusual presentations.
  • Typical symptoms include headaches, visual disturbances, and diplopia, but atypical signs may involve nerve palsies and other sensory issues.
  • The report highlights a rare case of fulminant IIH, marked by a sudden decline in vision accompanied by unilateral complete third nerve palsy.
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Eight-and-a-Half Syndrome Secondary to Acute Brainstem Infarction.

Cureus

July 2024

Department of Ophthalmology and Visual Science, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, MYS.

Eight-and-a-half syndrome is a rare neuro-ophthalmologic condition, which is characterized by ipsilateral horizontal gaze palsy, internuclear ophthalmoplegia (INO), and ipsilateral lower motor neuron facial palsy. We report a case of eight-and-a-half syndrome secondary to acute brainstem infarction. A 55-year-old gentleman with underlying diabetes mellitus and hypertension presented with a sudden onset of double vision in the right lateral gaze for one day.

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Ocular Manifestations of Multiple Sclerosis: A Population-Based Study.

J Neuroophthalmol

June 2024

Department of Ophthalmology (JAK, SCX, RF, FW, JJC), Mayo Clinic Hospital, Rochester, Minnesota; and Department of Neurology (EPF, JJC), Mayo Clinic Hospital, Rochester, Minnesota.

Background: To evaluate the population-based frequency and severity of multiple sclerosis (MS)-related ocular diseases.

Methods: Retrospective, population-based study examining patients with MS between January 1, 1998 and December 31, 2011. Patients were identified using the Rochester Epidemiology Project, which is a record-linkage system of medical records for all patient-physician encounters among Olmsted County, Minnesota residents.

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