This paper presents a nonlinear elastic material model able to simulate the nonlinear effects generated by the interaction of acoustic/ultrasonic waves with damage precursors and micro-cracks in a variety of materials. Such a constitutive model is implemented in an in-house finite element code and exhibits a multiscale nature where the macroscopic behavior of damaged structures can be represented through a contribution of a number of mesoscopic elements, which are composed by a statistical collection of microscopic units. By means of the semi-analytical Landau formulation and Preisach-Mayergoyz space representation, this multiscale model allows the description of the structural response under continuous harmonic excitation of micro-damaged materials showing both anharmonic and dissipative hysteretic effects. In this manner, nonlinear effects observed experimentally, such as the generation of both even and odd harmonics, can be reproduced. In addition, by using Kelvin eigentensors and eigenelastic constants, the wave propagation problem in both isotropic and orthotropic solids was extended to the three-dimensional Cartesian space. The developed model has been verified for a number of different geometrical and material configurations. Particularly, the influence of a small region with classical and non-classical elasticity and the variations of the input amplitudes on the harmonics generation were analyzed.
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http://dx.doi.org/10.1121/1.4868476 | DOI Listing |
JMIR Med Inform
January 2025
School of Software, Taiyuan University of Technology, Jingzhong, China.
Background: The prompt and accurate identification of mild cognitive impairment (MCI) is crucial for preventing its progression into more severe neurodegenerative diseases. However, current diagnostic solutions, such as biomarkers and cognitive screening tests, prove costly, time-consuming, and invasive, hindering patient compliance and the accessibility of these tests. Therefore, exploring a more cost-effective, efficient, and noninvasive method to aid clinicians in detecting MCI is necessary.
View Article and Find Full Text PDFThe American Heart Association's (AHA) Life's Essential 8 (LE8) metrics provide a framework for assessing cardiovascular health (CVH). This study evaluates the relationship between CVH levels from LE8 and mortality risk, considering biological aging's role. Using data from the NHANES non-CVD adult population, CVH scores were categorized as low (< 50), moderate (50-79), and high (≥ 80) per AHA guidelines.
View Article and Find Full Text PDFEcol Lett
January 2025
Department of Biology, Stanford University, Stanford, California, USA.
Predicting the effects of climate change on plant disease is critical for protecting ecosystems and food production. Here, we show how disease pressure responds to short-term weather, historical climate and weather anomalies by compiling a global database (4339 plant-disease populations) of disease prevalence in both agricultural and wild plant systems. We hypothesised that weather and climate would play a larger role in disease in wild versus agricultural plant populations, which the results supported.
View Article and Find Full Text PDFNanoscale
January 2025
School of Chemistry and Chemical Engineering, Center of Free Electron Laser & High Magnetic Field, Key Laboratory of Structure and Functional Regulation of Hybrid Materials Ministry of Education, Key Laboratory of Functional Inorganic Materials Chemistry of Anhui Province, and Key Laboratory of Chemistry for Inorganic/Organic Hybrid Functionalized Materials of Anhui Province, Anhui University, P.R. China.
Currently, the study of cuproptosis focuses on the Cu-induced morphology changes in mitochondria (Mito), and the observation of the effect of endoplasmic reticulum (ER)-related Cu content on cuproptosis is relatively lacking. Herein, we have developed a hydroxyflavone (HF)-based NIR excited two-photon fluorescent probe, BHCO, that exhibits specific recognition of Cu with high resolution. BHCO-Cu (Cu2BC) can lead to DLAT protein aggregation, triggering cuproptosis.
View Article and Find Full Text PDFJ Vet Emerg Crit Care (San Antonio)
January 2025
J. T. Vaughan Large Animal Teaching Hospital, Auburn University, Auburn, Alabama, USA.
Objective: To investigate the volume kinetic between 2 crystalloid fluid bolus rates in anesthetized cats.
Design: Prospective, randomized, dose-response study.
Setting: University laboratory.
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