AI Article Synopsis
- The study of senescent cells is crucial in aging research, but identifying these cells is challenging due to the complexity of senescence and the absence of a distinct marker.
- This chapter discusses various strategies for detecting senescent cells, particularly those adapted from mesenchymal cell research.
- It offers a detailed, step-by-step guide on using different techniques for the effective detection of senescent cells in laboratory settings.
Article Abstract
The detection of senescent cells has become an important area of research in the aging field. Due to the complexity of the senescence program and the lack of a unique signature for senescence, the detection of these cells remains problematic. This is especially true for in vivo detection in aged or diseased tissue samples. This chapter outlines approaches for the detection of senescent cells based upon methods established for mesenchymal cells in culture. A stepwise approach to the detection of senescent cells using multiple techniques is provided.
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| http://dx.doi.org/10.1007/978-1-4939-0888-2_23 | DOI Listing |
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