Limb gangrene in a neonate is an extremely rare clinical problem and bilateral symmetrical lower limbs type is even rarer. Only few clinical cases have been reported thus far with idiopathic etiology or associated with rare conditions. Known causes in literature are sepsis, extravasation of intravenous fluid, following a complicated delivery and secondary to invasive monitoring. This report describes neonate was first developed sepsis and later was exposed to cold leading to bilateral gangrene of lower limbs.

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