The aim of the present study was to evaluate the uptake and intracellular destruction capacity of the human neutrophil. Human neutrophils from healthy individuals not receiving any therapy were incubated during 15, 90 and 180 minutes with the minimal, intermediate and maximal doses achieved in serum during treatment with therapeutic doses of these antibiotics (3, 6.45 and 9.9 micrograms/ml of erythromycin and 30, 45 and 60 micrograms/ml of phosphomycin). After this incubation, the uptake capacity and the intracellular destruction capacity of Candida guillermondii by neutrophils was assessed. Both erythromycin and phosphomycin maintained the baseline levels of both capacities in all the incubations evaluated. In addition, during the incubation with maximal dose erythromycin (15 min) a stimulatory tendency of the uptake and intracellular destruction capacity was observed.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Common insect pests in homes and cultural heritage sites.
PeerJ
January 2025
IHU Méditerranée Infection, Marseille, Provence-Alpes-Côte d'Azur, France.
Insect pests represent a threat to the integrity of historic buildings and homes, causing serious losses and irreversible damage. These pests can cause extensive damage to organic materials, including wood, textiles, and paper. Beetles, termites, booklice, moths, and cockroaches are just some of the main insect pests that are frequently found in historic buildings and homes.
View Article and Find Full Text PDFPFAS Destruction and Near-Complete Defluorination of Undiluted Aqueous Film-Forming Foams at Ambient Conditions by Piezoelectric Ball Milling.
Environ Sci Technol
January 2025
Department of Civil and Environmental Engineering, Clarkson University, Potsdam, New York 13699, United States.
The nonthermal destruction of aqueous film-forming foam (AFFF) stockpiles, one of the major culprits responsible for water and soil contamination by per- and polyfluoroalkyl substances (PFAS), is extremely challenging because of the coexistence of mixed recalcitrant PFAS and complicated organic matrices at extremely high concentrations. To date, the complete defluorination of undiluted AFFF at ambient conditions has not been demonstrated. This study reports a novel piezoelectric ball milling approach for treating AFFF with a total organic fluorine concentration of 9080 mg/L and total organic carbon of 234 g/L.
View Article and Find Full Text PDFEffects of leading-edge serration shape on noise reduction in rod-airfoil interactions.
J Acoust Soc Am
January 2025
Department of Modern Mechanics, University of Science and Technology of China, Hefei 230027, China.
Leading-edge serrations inspired by owls exhibit the capability to control airfoil-turbulence interaction noise, but the design principle of the serration shape is still an open issue. To this end, we designed five types of serration shapes with different combinations of curvature, namely, triangular, ogee, anti-ogee, feather-like, and anti-feather-like. These curves are applied to serrated modifications with different bluntness levels (sharp or blunt) and amplitudes (0.
View Article and Find Full Text PDFFerritin From Striped Stem Borer (Chilo suppressalis) Oral Secretion Acts as an Effector Helping to Maintain Iron Homoeostasis and Impair Defenses in Rice.
Plant Cell Environ
January 2025
Institute of Plant Protection, Jiangsu Academy of Agricultural Sciences, Jiangsu Key Laboratory for Food and Safety, State Key Laboratory Cultivation Base of Ministry of Science and Technology, Nanjing, China.
The striped stem borer (Chilo suppressalis, SSB) is a highly destructive insect pest in rice (Oryza sativa). SSB oral secretions (OSs) can induce plant defense responses in rice. However, the specific effectors in SSB OSs that mediate these interactions with rice remain poorly understood.
View Article and Find Full Text PDFMitochondrial Dysfunction in Diabetic Periodontitis: Mechanisms and Therapeutic Potential.
J Inflamm Res
January 2025
Anhui Province Engineering Research Center for Dental Materials and Application, School of Stomatology, Wannan Medical College, Wuhu, 241002, People's Republic of China.
Diabetic periodontitis is a common oral complication of diabetes characterized by progressive destruction of periodontal tissues. Recent evidence suggests that mitochondrial dysfunction plays a crucial role in the pathogenesis and progression of this condition. This review aims to systematically summarize the role and potential mechanisms of mitochondrial dysfunction in diabetic periodontitis.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!