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One hundred and twenty cases of enduring sexual dysfunction following treatment. | LitMetric

One hundred and twenty cases of enduring sexual dysfunction following treatment.

Int J Risk Saf Med

David Braley & Nancy Gordon Chair of Family Medicine, Department of Family Medicine, McMaster University, ON, Canada.

Published: February 2015

AI Article Synopsis

  • The study investigates the long-term sexual dysfunction associated with serotonin reuptake inhibitors, finasteride, and isotretinoin, collecting data from 120 reports from RxISK.org.* -
  • Findings indicate that these three drugs share a similar range of symptoms experienced by both men and women, regardless of their geographic location.* -
  • The research highlights the seriousness of this enduring condition, emphasizing the need for further understanding of its causes and effective treatment options.*

Article Abstract

Background: There have been reports for over a decade linking serotonin reuptake inhibitors, finasteride and isotretinoin with enduring sexual dysfunction after treatment stops.

Objective: To explore the clinical pictures linked to all 3 drugs.

Methods: We have selected 120 reports to RxISK.org reporting the problem and mined these for data on age, gender, drug of use, and impact of the problem.

Results: The data make it clear that the three drugs show extensive overlap in symptom profile, regardless of sex or country of origin.

Conclusions: The availability of 120 reports from over 20 countries add to the case for the validity of the syndrome. This is severe and enduring condition can result in death. An understanding of its physiology and an approach to treatment are needed.

Download full-text PDF

Source
http://dx.doi.org/10.3233/JRS-140617DOI Listing

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