The association between aflatoxin intake from maize-based weaning food and aflatoxin albumin adducts (AF-alb) was investigated in 148 Tanzanian children aged between 12 and 22 months, at 2 visits 6 months apart. At the first visit (storage season) there was a significant correlation at the individual level between AF-alb (geometric mean 43.2 pg/mg albumin) and aflatoxin intake (geometric mean 81.7 ng/kg b.w./d) through maize-based weaning food (r = 0.51, p < 0.01). Overall, this correlation was r = 0.43 (p < 0.01). The AF-alb level in weaning-age children in Tanzania closely reflects aflatoxin intake from maize in weaning food. Exposure levels suggest children may be at risk from aflatoxin associated health effects.
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http://dx.doi.org/10.3109/1354750X.2014.924998 | DOI Listing |
Front Public Health
January 2025
School of Public Health, Guangdong Pharmaceutical University, Guangzhou, China.
Background: Aflatoxin B (AFB), a potent carcinogen produced by species, is a prevalent contaminant in oil crops, with prolonged exposure associated with liver damage. Home-made peanut oil (HMPO) produced by small workshops in Guangzhou is heavily contaminated with AFB. Despite the enactment of the Small Food Workshops Management Regulations (SFWMR), no quantitative assessment has been conducted regarding its impact on food contamination and public health.
View Article and Find Full Text PDFAm J Clin Nutr
December 2024
Center for Research on Population Health, National Institute of Public Health, Cuernavaca, Mexico; Department of Global Health and Population, Harvard T.H. Chan School of Public Health, Boston, MA, United States. Electronic address:
Background: Maize is frequently contaminated by aflatoxin B (AFB), an established liver carcinogen.
Objectives: The objective of this study is to estimate the effect of maize and maize tortilla consumption on AFB-lysine adduct (AFB-lys) concentrations in middle- and older-aged adults living in south and eastern Mexico.
Methods: We conducted a cross-sectional analysis in a representative sample of 915 adults aged ≥40 y living in south and eastern Mexico in 2018-2019.
Environ Monit Assess
December 2024
Department of Biology, Faculty of Science, Eskişehir Osmangazi University, Eskişehir, 26040, Turkey.
Environmental pollution is a problem that affects food safety throughout the world. In this study, a health risk assessment of possible toxic metal and aflatoxin contamination in homemade and industrial noodles produced in Türkiye was carried out. Samples were taken from 67 kinds of homemade and five kinds of industrial noodles from different cities.
View Article and Find Full Text PDFJDS Commun
November 2024
Department of Animal Science, Iowa State University, Ames, IA 50011.
Aflatoxin M (AFM) is a pathogenic metabolite transferred from feed into milk from aflatoxin (AF) B, B, G, and G; thus, it poses a human health risk. Therefore, effective mitigation strategies are needed to reduce animal and human exposure to AF. Study objectives were to evaluate a dietary adsorbent (Silicoglycidol, ATX) as a sequestering agent in AF-contaminated feed and to broadly examine how AF affects liver function and the immune system.
View Article and Find Full Text PDFArch Toxicol
December 2024
Institute of Food Chemistry, University of Münster, Corrensstraße 45, 48149, Münster, Germany.
Toxic fungal secondary metabolites, referred to as mycotoxins, emerge in moldy food and feed and constitute a potent but often underestimated health threat for humans and animals. They are structurally diverse and can cause diseases after dietary intake even in low concentrations. To elucidate cellular responses and identify cellular targets of mycotoxins, a bottom-up proteomics approach was used.
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