Objectives: To summarize the current knowledge relating to diagnosing and treating Scheuermann's disease. Scheuermann's disease is the most common cause of structural kyphosis in adolescence.
Methods: A literature-based narrative review of English language medical literature.
Results And Conclusions: Recent studies have revealed a major genetic contribution (a dominant autosomal inheritance pattern with high penetrance and variable expressivity) to the etiology of Scheuermann kyphosis with a smaller environmental component (most probably mechanical factors). The natural history of Scheuermann kyphosis remains controversial, with conflicting reports as to the severity of pain and physical disability. Since we cannot predict which kyphotic curves will progress, we are unable to determine effectiveness of brace treatment. Physical therapy is scarcely mentioned in the literature as an effective treatment for Scheuermann kyphosis. Although there is little evidence that physical therapy alone can alter the natural history of Scheuermann's disease, it is often used as the first choice of treatment. Brace treatment appears to be more effective if an early diagnosis is made, prior to the curvature angle exceeding 50° in patients continuing to grow. Surgical treatment is rarely indicated for severe kyphosis (>75°) with curve progression, refractory pain, or a neurologic deficit. Rigorous methodology clinical trials are essential to evaluate the efficacy of conservative interventions, especially different exercises and manual therapies and their combinations with braces.
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http://dx.doi.org/10.3233/BMR-140483 | DOI Listing |
Ann Surg Open
December 2024
From the Department of Visceral, Transplant, Thoracic and Vascular Surgery, Division of Hepatobiliary Surgery and Visceral Transplant Surgery, University Clinic Leipzig, Germany.
Objective: This study explored the novel application of hyperspectral imaging (HSI) for in vivo allograft perfusion assessment during liver transplantation (LT) and its potential value for predicting early allograft dysfunction (EAD), graft, and overall survival (OS).
Background: LT is a well-established therapy for acute and chronic liver diseases, with excellent outcomes. However, a significant proportion of recipients experience EAD, which affects graft and OS.
Rev Bras Ortop (Sao Paulo)
December 2024
Departamento de Ortopedia e Anestesiologia, Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brasil.
The aim of the present study was to detect atypical Scheuermann's disease through computed tomography scans and estimate its prevalence. This cross-sectional observational study involved 1,287 computed tomography scans from patients aged 18 to 40 years of both genders. The criteria for diagnosing atypical Scheuermann's disease included wedging of 5° in 3 consecutive vertebrae, combined with a total Cobb angle of 10° or more within the thoracolumbar interval from T8 to L2.
View Article and Find Full Text PDFEur Spine J
December 2024
Pediatric Orthopedics Unit, Pediatric Surgery Service, Geneva University Hospitals and University of Geneva, Geneva, Switzerland.
Purpose: Evaluate the validity of rasterstereography compared to low-dose, biplanar spine radiography for assessing thoracic kyphosis (TK) angles in Scheuermann's disease patients.
Methods: This prospective study included all the Scheuermann's disease patients consulting our clinic from 2016 to 2018. Recruited patients underwent two-dimensional low-dose biplanar anteroposterior full-length spine radiography and rasterstereography on the same day.
J Alzheimers Dis
December 2024
Center for Health Services Research in Medicine, Department of Psychiatry and Psychotherapy, Uniklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.
Background: Mild cognitive impairment (MCI) and mild behavioral impairment (MBI) are both considered potential prodromal stages of dementia, especially Alzheimer's disease. Previous literature has lacked specific information about MBI in individuals with MCI and associations of several aspects of both, MBI and MCI.
Objective: Our aim was to investigate whether associations exist between aspects of MBI and aspects of cognitive performance in certain dimensions of the Montreal Cognitive Assessment (MoCA).
PLoS One
November 2024
Department of Biology, The King's University, Edmonton, Alberta, Canada.
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