Mild cognitive impairment diagnosed with the new DSM-5 criteria: prevalence and associations with non-cognitive psychopathology.

Acta Psychiatr Scand

Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Ministry of Science and Innovation, Madrid, Spain; Department of Psychology and Sociology, Universidad de Zaragoza, Zaragoza, Spain.

Published: January 2015

AI Article Synopsis

  • The study compares the prevalence of mild cognitive impairment (MCI) diagnosed by DSM-5 criteria and Petersen's criteria, finding that DSM5-MCI occurs in 3.72% of individuals aged 65+ while P-MCI occurs in 7.93%.
  • The research included a sample of over 4,800 seniors and utilized various diagnostic tools to assess mental health and associated symptoms like anxiety and depression.
  • Results indicate that negative non-cognitive psychopathological symptoms are more common in DSM5-MCI cases, whereas affective symptoms primarily relate to P-MCI.

Article Abstract

Objective: To contrast the prevalence of mild cognitive impairment (MCI) as diagnosed using DSM-5 criteria (DSM5-MCI) with MCI as diagnosed using Petersen's criteria (P-MCI) and to explore the association of both with non-cognitive psychopathological symptoms (NCPS).

Method: A two-phase epidemiological screening was implemented in a population-based sample of individuals aged 55+ (n = 4803). The Geriatric Mental State (GMS) was the main psychopathological instrument used, and AGECAT was used to make psychiatric diagnoses. Research psychiatrists diagnosed DSM5-MCI and P-MCI using operational criteria. Logistic regression models were then used to investigate the association of MCI with anxiety and depression and with NCPS.

Results: Weighted prevalence of DSM5-MCI and P-MCI was, respectively, 3.72% and 7.93% for the aged 65+. NCPS were common in both MCI categories, but negative-type symptoms such as 'anergia' and 'observed slowness' were considerably more frequent among persons with DSM5-MCI. Anxiety and depression diagnostic categories were associated with both P-MCI and DSM5-MCI, but affective-type symptoms were mainly associated with P-MCI. Some negative-type symptoms were inversely associated with P-MCI, and no association was observed with DSM5-MCI.

Conclusion: The prevalence of DSM5-MCI was half that of P-MCI. Negative-type NCPS were more frequently and typically associated with DSM5-MCI.

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http://dx.doi.org/10.1111/acps.12297DOI Listing

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