Candida speciation, antifungal treatment and adverse events in pediatric invasive candidiasis: results from 441 infections in a prospective, multi-national study.

Pediatr Infect Dis J

From the *Baylor College of Medicine and Texas Children's Hospital, Houston, TX; †Children's Hospital of Orange County, Orange, CA; ‡Istituto Giannina Gaslini, Genova, Italy; §Monroe Carell Jr. Children's Hospital at Vanderbilt University, Nashville, TN; ¶Children's Hospital of Philadelphia, Philadelphia, PA; and ‖Duke University, Durham, NC.

Published: December 2014

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Article Abstract

A multi-national prospective study of pediatric patients with invasive candidiasis between August 2007 and September 2012 was performed and included 441 infections. Variation in infecting Candida species and antifungals used was noted between US and non-US sites. Antifungal-associated adverse events were most common with polyene use.

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http://dx.doi.org/10.1097/INF.0000000000000431DOI Listing

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