UV phototherapy has a long history of use for the treatment of select diseases in dermatology. Its use has evolved into more effective and targeted modalities, including psoralen + UV-A photochemotherapy, narrowband UV-B, excimer laser, and UV-A1 phototherapy. With its proven record of efficacy and safety, UV phototherapy is an excellent option in the treatment of an ever-growing number of skin conditions.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.det.2014.03.003 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Identification of new inhibitors of Plasmodium falciparum hypoxanthine-guanine-xanthine Phosphoribosyltransferase (HG(X)PRT): An outlook towards the treatment of malaria.
Int J Biol Macromol
January 2025
Dr. Panjwani Center for Molecular Medicine and Drug Research, International Center of Chemical and Biological Sciences, University of Karachi, Karachi 75270, Pakistan; H. E. J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi 75270, Pakistan; Department of Biochemistry, Faculty of Sciences, King Abdulaziz University, Jeddah 22252, Saudi Arabia. Electronic address:
Article Synopsis
- Plasmodium, the parasite causing malaria, relies on the purine salvage pathway for survival, making its enzymes, like HGXPRT, potential targets for new antimalarial drugs.
- The study focused on inhibiting HGXPRT to disable the parasite's nucleotide synthesis, optimizing assays to evaluate over 200 compounds for their inhibitory effects.
- Fourteen compounds were identified as effective inhibitors, with promising interactions at the enzyme's binding site, and they were shown to be non-toxic to human cells, setting the stage for further drug development.
Risk of infection due to airborne virus in classroom environments lacking mechanical ventilation.
PLoS One
November 2024
Department of Life Sciences, Long Island University Post, Brookville, NY, United States of America.
The COVID-19 pandemic highlighted the role of indoor environments on disease transmission. However, our understanding of how transmission occurred evolved as the pandemic progressed. Enclosed spaces where pathogen-laden aerosols accumulate were strongly linked to increased transmission events.
View Article and Find Full Text PDFDetermination of anamorelin concentration in human plasma using a simple high-performance liquid chromatography-ultraviolet detection method.
Drug Discov Ther
September 2024
Department of Respiratory Medicine, Tokyo Metropolitan Bokutoh Hospital, Tokyo, Japan.
Article Synopsis
- - Anamorelin is an oral drug designed to treat cancer cachexia, a condition often seen in cancer patients, and it interacts with the liver enzyme CYP3A4, which can lead to drug-drug interactions.
- - The study developed a high-performance liquid chromatography-ultraviolet (HPLC-UV) method to measure anamorelin levels in human plasma, focusing on sample preparation and accurate separation using specific chemical conditions.
- - The method showed a strong calibration curve and good precision and accuracy, suggesting it could be effectively used in clinical settings to monitor anamorelin concentration.
The burning truth about light therapy: a retrospective analysis of the MAUDE database on UV phototherapy and photodynamic therapy complications 2013-2023.
Arch Dermatol Res
December 2023
Department of Dermatology, Weill Cornell Medicine, 1305 York Avenue, New York, NY, 10021, USA.
Introduction: Phototherapy and photodynamic therapy (PDT) are ultraviolet light (UV) based therapies for patients with skin diseases, and are sometimes associated with potential adverse events (AE)s, including erythema, pain, pruritus, burns, and photoaging.
Methods: We investigated UV phototherapy and PDT safety using the United States (US) Food and Drug Administration's (FDA)'s Manufacturer and User Facility Device Experience (MAUDE) database. The MAUDE database, including medical device reports (MDR)s informed by voluntary and obligatory reporters since 1991, was searched for AEs associated with UV phototherapy and PDT 1/1/91-3/1/23.
Phototherapy for atopic dermatitis: A survey of European practice.
J Eur Acad Dermatol Venereol
March 2024
Unit for Paediatric and Population-Based Dermatology Research, St John's Institute of Dermatology, Guy's and St Thomas' NHS Foundation Trust and King's College London, London, UK.
Background: Phototherapy is used to treat atopic dermatitis (AD). Evidence for its efficacy, impact on quality of life, cost-effectiveness and short- and long-term safety with real-life usage is weak.
Objectives: We established a taskforce to examine how phototherapy is currently being used as a treatment for AD across the United Kingdom and Europe to inform our understanding and guide future research into management of patients with AD using UV-based phototherapies.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!