The lipase catalyzed resolution of cis and trans-3-amino-4-hydroxytetrahydrofurans and cis-3-amino-4-hydroxypyrrolidines have been studied. For all the heterocycles, the best enantioselectivity was obtained using Candida antarctica lipases A and B as catalysts in hydrolytic processes. The absolute configuration of the optically pure obtained heterocycles has been assigned.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.bmc.2014.05.014 | DOI Listing |
Publication Analysis
Top Keywords
cis trans-3-amino-4-hydroxytetrahydrofurans
8
trans-3-amino-4-hydroxytetrahydrofurans cis-3-amino-4-hydroxypyrrolidines
8
enzymatic preparation
4
preparation cis
4
cis-3-amino-4-hydroxypyrrolidines lipase
4
lipase catalyzed
4
catalyzed resolution
4
resolution cis
4
cis-3-amino-4-hydroxypyrrolidines studied
4
studied heterocycles
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!