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Matrix-assisted peptide synthesis on nanoparticles. | LitMetric

Matrix-assisted peptide synthesis on nanoparticles.

J Pept Sci

Department of Chemistry, Laboratory of Nano-Biomaterials, Bar Ilan University, Ramat Gan, 52900, Israel.

Published: September 2014

We report a new method for multistep peptide synthesis on polymeric nanoparticles of differing sizes. Polymeric nanoparticles were functionalized via their temporary embedment into a magnetic inorganic matrix that allows multistep peptide synthesis. The matrix is removed at the end of the process for obtaining nanoparticles functionalized with peptides. The matrix-assisted synthesis on nanoparticles was proved by generating various biologically relevant peptides.

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Source
http://dx.doi.org/10.1002/psc.2664DOI Listing

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