Ultrastructural fingerprints of avian influenza A (H7N9) virus in infected human lung cells.

Virology

Virologie et Pathologie Humaine VirPath, EA 4610, Université Claude Bernard Lyon 1-Hospices Civils de Lyon, Lyon, France; VirNext, Faculté de Médecine RTH Laennec, Université Lyon 1, Lyon, France. Electronic address:

Published: May 2014

In this study, we investigated the ultrastructural modifications induced by influenza A (H7N9) virus in human lung epithelial cells. One particular characteristic of H7N9 viral infection is the formation of numerous M1-associated striated tubular structures within the nucleus and the cytoplasm, which have only previously been observed for a limited number of influenza A viruses, notably the 2009 pandemic (H1N1) virus.

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Source
http://dx.doi.org/10.1016/j.virol.2014.03.013DOI Listing

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