We compared the effectiveness and stability of our first six consecutive myopic epikeratophakia procedures (mean follow-up 18 months, range 14 to 26) with our first four consecutive cryolathe myopic keratomileusis procedures (mean follow-up 28 months, range 14 to 35). Myopic keratomileusis reduced preoperative myopia (range -8.9 to -12.1 diopters) by 77% to 94% in four patients. Refraction and visual acuity remained stable for over 1 to 3 years. In contrast, only three of the six myopic epikeratophakia procedures had stable results. The remaining three eyes which were within 0.38 D of emmetropia at the time of suture removal showed a loss of effect, resulting in myopia worse than their preoperative values in two eyes and a small correction in one eye. Only one of the six eyes achieved an uncorrected visual acuity better than 20/200. We conclude that myopic keratomileusis may be the procedure of choice for treating individuals with myopia of -8 to -15 D, because the incidence of late regression of effect after myopic epikeratophakia using the techniques in this study is unacceptable.
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Cornea
January 2025
Institut für Refraktive und Ophthalmo-Chirurgie (IROC), Zurich, Switzerland.
Purpose: To describe a three-phase surgical approach for managing progressive visual decline in a patient with myopia magna and a history of epikeratophakia.
Methods: A 55-year-old woman with previous epikeratophakia surgery in both eyes experienced progressive visual deterioration. The three-phase approach included: (1) removal of the epikeratophakia lenticule, (2) cataract extraction with intraocular lens implantation, and (3) transepithelial topography-guided photorefractive keratectomy (trans-PRK).
Indian J Ophthalmol
December 2020
Department of Ophthalmology and Visual Neurosciences, University of Minnesota; Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN, USA.
We report the clinical history and histopathology of the longest known postoperative course of a myopic cornea lenticule implanted via epikeratoplasty that also had been subjected to excimer laser and mitomycin. Despite the mechanical and photochemical processes the allogenic cornea stroma had sustained, it is notable that it retained structural integrity and clarity. This report affirms the potential long-term clarity and resilience of allogenic stromal cornea and supports its use as a potential stabilizing option in cornea allogenic intrastromal ring segments for keratoconus and variations thereof for other cornea disorders.
View Article and Find Full Text PDFPurpose: To describe the visual outcomes of correcting moderate to high hyperopia after two different surgical procedures of lenticular implantation.
Methods: This prospective small case series study used epikeratophakia combined with transepithelial phototherapeutic keratectomy (PTK-EP) and femtosecond laser-assisted lenticule intrastromal keratoplasty (LIKE) using myopic small incision lenticule extraction (SMILE)-derived refractive lenticule for correcting hyperopia ranging from +3.00 to +10.
J Cataract Refract Surg
August 2019
Department of Ophthalmology, Eye and ENT Hospital, Fudan University, the NHC Key Laboratory of Myopia, the Laboratory of Myopia, Chinese Academy of Medical Science, and the Shanghai Research Center of Ophthalmology and Optometry, Shanghai, China. Electronic address:
An 18-year-old man with keratoconus had epikeratophakia using small-incision lenticule extraction lenticule addition in the left eye, which had a minimum corneal thickness of 356 μm. Accelerated (45 mW/cm) transepithelial corneal crosslinking was performed 1 month later. The patient was followed for 3 years postoperatively.
View Article and Find Full Text PDFCornea
March 2018
Zhongshan Ophthalmic Center, State Key Laboratory of Ophthalmology, Sun Yat-Sen University, Guangzhou, China.
Purpose: To evaluate the feasibility and safety of xenogeneic endokeratophakia in rhesus monkeys and to explore the effects of a concave lenticule on refractive power.
Methods: Three adult New Zealand white rabbits and 6 healthy rhesus monkeys were used. The xenogenic concave grafts were created from the rabbits using a modified small incision lenticule extraction technique; after being cryopreserved in glycerol for 1 week, the grafts were implanted into the monkey recipient corneas.
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