Sudden cardiac death in a dialysis patient: hyperkalemia reconsidered.

J Emerg Med

Emergency Department, State University of New York Downstate, Kings County Hospital, Brooklyn, New York.

Published: September 2014

Background: To many physicians, hyperkalemia is the first diagnosis ascribed to any patient with end-stage renal disease and abnormal electrocardiographic morphologies or dysrhythmias.

Case Report: A 52-year-old man with end-stage renal disease presented in cardiac arrest. The patient was initially presumed to have hyperkalemia, based on the appearance of wide QRS complexes on the monitor. The diagnosis of hyperkalemia was incorrect; the patient was severely hypokalemic and suffered recurrent episodes of ventricular fibrillation and torsades de pointes.

Why Should An Emergency Physician Be Aware Of This: An emergency physician's differential diagnosis of sudden cardiac arrest in the patient with end-stage renal disease should not be limited to hyperkalemia and myocardial infarction. Hypokalemia should also be considered. Hypokalemia may be an under-recognized cause of sudden cardiac death in this patient population.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jemermed.2014.04.025DOI Listing

Publication Analysis

Top Keywords

sudden cardiac
12
end-stage renal
12
renal disease
12
cardiac death
8
patient end-stage
8
cardiac arrest
8
arrest patient
8
patient
6
hyperkalemia
5
death dialysis
4

Similar Publications

Loss-of-function SLC25A20 mutation causes carnitine-acylcarnitine translocase deficiency by reducing SLC25A20 protein stability.

Gene

December 2024

Department of Medical Genetics/Experimental Education/Administration Center, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China; Guangdong Provincial Key Laboratory of Single Cell Technology and Application, Guangzhou 510515, China; Department of Fetal Medicine and Prenatal Diagnosis, Zhujiang Hospital, Southern Medical University, Guangzhou 510280, China. Electronic address:

Background/aim: Autosomal-recessive carnitine-acylcarnitine translocase deficiency (CACTD) is a rare disorder of long-chain fatty acid oxidation caused by variants in the SLC25A20 gene. Under fasting conditions, most newborns with severe CACTD experience sudden cardiac arrest and hypotonia, often leading to premature death due to rapid disease progression. Understanding of genetic factors and pathogenic mechanisms in CACTD is essential for its diagnosis, treatment, and prevention.

View Article and Find Full Text PDF

Background -Smoking is associated with arrhythmia and sudden cardiac death, but the biological mechanisms remain unclear. In electrocardiogram (ECG) recordings abnormal durations of ventricular repolarization (QT interval), atrial depolarization (P wave), and atrioventricular depolarization (PR interval and segment), predict cardiac arrhythmia and mortality. Previous analyses of the National Health and Nutrition Examination Survey (NHANES) database for associations between smoking and ECG abnormalities were incomplete.

View Article and Find Full Text PDF

Background Neonatal vascular air embolism is a rare but often fatal condition. The literature comprises mostly case reports and a few dated systematic reviews. Our objective was to review all case reports of neonatal vascular air embolism to date, and provide up-to-date information about patient characteristics, clinical presentations, outcomes, pathogenesis, diagnosis, prevention, treatment and prognosis.

View Article and Find Full Text PDF

Causes of Death Following Coronary Revascularization in Patients with Diabetes.

Ann Thorac Surg

December 2024

Cedars-Sinai Health System, Los Angeles, CA, USA. Electronic address:

Background: In patients with diabetes and multivessel coronary artery disease, percutaneous coronary intervention (PCI) has been associated with higher long-term cardiovascular mortality compared to coronary artery bypass grafting (CABG), but the specific causes of death are not well known. We aimed to determine the causes of death among patients with diabetes and multivessel disease undergoing coronary revascularization with PCI versus CABG.

Methods: We analyzed the centrally adjudicated causes of death of 1,900 participants in the FREEDOM trial.

View Article and Find Full Text PDF

Cardiovascular magnetic resonance in patients with mitral valve prolapse.

J Cardiovasc Magn Reson

December 2024

School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, London, UK.

With a prevalence of 2-3% in the general population, mitral valve prolapse (MVP) is the most common valvular heart disease. The clinical course is benign in the majority of patients, although severe mitral regurgitation, heart failure, and sudden cardiac death affect a non-negligible subset of patients. Imaging of MVP was confined to echocardiography until a few years ago when it became apparent that cardiovascular magnetic resonance (CMR) could offer comparative advantages for detecting and quantifying mitral valve abnormalities alongside tissue myocardial characterization.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!