Three novel degraded steroids from cultures of the Basidiomycete Antrodiella albocinnamomea.

Steroids

State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, People's Republic of China. Electronic address:

Published: September 2014

Three novel degraded steroids, named albocisterols A-C (1-3), have been isolated from cultures of Antrodiella albocinnamomea. Their structures were defined by comprehensive spectroscopic analysis and single crystal X-ray crystallography. The mixture of compounds 2 and 3 exhibited significant inhibitory activities against protein tyrosine phosphatase 1B (PTP1B).

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http://dx.doi.org/10.1016/j.steroids.2014.05.008DOI Listing

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