Eosinophilic fasciitis is an uncommon entity characterized by edema, skin thickening and hyperpigmentation of extremities. Laboratory findings are variable and may include hypergammaglobulemia, peripheral eosinophilia and elevated acute phase reactants. A full-thickness skin/fascia/muscle biopsy is the gold standart for diagnosis. Since EF is an uncommon disorder and the clinic presentation mimics scleroderma, it takes a long time to make definitive diagnosis. We present a case diagnosed two years after its onset and responded well to the treatment. We also include herein the results of our literature survey regarding delayed diagnosis of Eosinophilic Fasciitis.
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ACR Open Rheumatol
January 2025
Shanghai Sixth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
ARP Rheumatol
January 2024
Unidade Local de Saúde do Alto Minho.
Eur J Nucl Med Mol Imaging
December 2024
Nuclear Medicine Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Dermatol Reports
November 2024
Department of Dermatology, San Bortolo Hospital, Vicenza, Italy.
Eosinophilic fasciitis (EF) poses a diagnostic challenge owing to its uncommon occurrence and aetiology that remains poorly understood. We report a case of a 79-year-old woman with a prolonged history of breast cancer exhibiting EF with concomitant pelvic metastases. This case underscores EF's potential as an indicator signaling a potential resurgence of cancer, highlighting its significance as a red flag of disease recurrence.
View Article and Find Full Text PDFA 61 year old male presented with clinical signs of Eosinophilic fasciitis (EF), a rare connective tissue disease. Early recognition of the diagnosis of EF is essential. Common examination findings are prayer sign and distal limb swelling, induration, venous guttering, and peau d'orange.
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