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Hypotensive Episodes Identified on 24-Hour Ambulatory Blood Pressure and Impaired Cognitive Function: Insights From the SPRINT Study.
Hypertension
January 2025
Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA (W.Z., D.H., M.A.M., Y.M.).
Background: Hypotensive episodes detected by 24-hour ambulatory blood pressure (BP) monitoring capture daily cumulative hypotensive stress and could be clinically relevant to cognitive impairment, but this relationship remains unclear.
Methods: We included participants from the Systolic Blood Pressure Intervention Trial (receiving intensive or standard BP treatment) who had 24-hour ambulatory BP monitoring measured near the 27-month visit and subsequent biannual cognitive assessments. We evaluated the associations of hypotensive episodes (defined as systolic BP drops of ≥20 mm Hg between 2 consecutive measurements that reached <100 mm Hg) and hypotensive duration (cumulative time of systolic BP <100 mm Hg) with subsequent cognitive function using adjusted linear mixed models.
Touch-driven advantages in reaction time but not in performance in a cross-sensory comparison of reinforcement learning.
Heliyon
January 2025
Centre for Tactile Internet with Human-in-the-Loop (CeTI), 6G Life, Technische Universität Dresden, Germany.
Recent research has highlighted a notable confidence bias in the haptic sense, yet its impact on learning relative to other senses remains unexplored. This online study investigated learning behaviour across visual, auditory, and haptic modalities using a probabilistic selection task on computers and mobile devices, employing dynamic and ecologically valid stimuli to enhance generalisability. We analysed reaction time as an indicator of confidence, alongside learning speed and task accuracy.
View Article and Find Full Text PDFA hybrid human fall detection method based on modified YOLOv8s and AlphaPose.
Sci Rep
January 2025
Human-Computer Collaborative Robot Joint Laboratory of Anhui Province, Huainan, China.
To address the challenges of low detection accuracy of small objects and weak applicability of the multi-person fall action recognition applications, we propose a hybrid fall detection method based on modified YOLOv8s and AlphaPose called HFDMIA-Pose. Firstly, we use the modified Yolov8s as object detector. It uses SPD-Conv to preserve small object features and adds a small object detection layer, while using BCIOU as the loss function.
View Article and Find Full Text PDFThe Impact of Ankle Plantar-Flexor Muscle Strength on Sprint Acceleration in Floorball Players.
Int J Sports Physiol Perform
January 2025
Faculty of Education Sciences and Physiology, University of Latvia, Riga, Latvia.
Purpose: Speed is a crucial physical characteristic where each lower-limb ankle plantar-flexor (PF) muscle needs to generate significant force; however, there is limited evidence about the relationship between single-limb isometric, and reactive strength forms, and linear sprint. The aim of this study was to determine the impact of the maximal unilateral isometric strength of the ankle PF muscle and reactive strength on sprint acceleration performance.
Material And Methods: Thirty-two male floorball players (mean [SD] age 20.
A randomized controlled trial comparing embryo vitrification with slush nitrogen to liquid nitrogen in women undergoing frozen embryo transfer: embryology and clinical outcomes.
Hum Reprod
January 2025
IVIRMA Global Research Alliance, IVIRMA New Jersey, Basking Ridge, NJ, USA.
Study Question: Does the use of slush nitrogen (SN) for embryo vitrification improve embryo transfer outcomes compared to liquid nitrogen (LN)?
Summary Answer: SN is a safe method for embryo preservation and significantly improves post-warming survival rates during repeated vitrification-warming cycles; however, after a single freeze-thaw cycle, pregnancy outcomes are not improved when embryos are vitrified with SN compared to LN.
What Is Known Already: SN is a combination of solid and LN, with a temperature lower than regular LN, and it is an alternative to conventional LN in achieving a faster cooling speed. Studies have shown that SN improves survival in non-human embryos and human oocytes.
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