AI Article Synopsis
- The introduction of genome-wide association studies (GWAS) has advanced the understanding of the genetic factors contributing to refractive error and myopia.
- Multiple GWAS across diverse ethnic groups have revealed insights into the genetic structure and underlying causes of refractive error.
- The review discusses the key findings from existing GWAS and suggests future avenues for further genetic research in myopia and refractive error.
Article Abstract
The investigation of the genetic basis of refractive error and myopia entered a new stage with the introduction of genome-wide association studies (GWAS). Multiple GWAS on many ethnic groups have been published over the years, providing new insight into the genetic architecture and pathophysiology of refractive error. This is a review of the GWAS published to date, the main lessons learned, and future possible directions of genetic studies of myopia and refractive error.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039381 | PMC |
| http://dx.doi.org/10.1167/iovs.14-14149 | DOI Listing |
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