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[Epileptic seizures in patients with systemic rheumatic disorders]. | LitMetric

[Epileptic seizures in patients with systemic rheumatic disorders].

Zh Nevrol Psikhiatr Im S S Korsakova

Kafedra nevrologii i meditsinskoĭ genetiki s kursom neĭrokhirurgii GBOU VPO "Iaroslavskaia gosudarstvennaia meditsinskaia akademiia", Iaroslavl'

Published: January 2014

Systemic rheumatic disorders affect multiple organ systems. Seizures are among the most common neurological manifestation and occasionally can be the presenting symptom. This article reviews the literature on the mechanisms underlying seizures in systemic rheumatic disorders and predisposing factors, including vascular disease (e.g., prothrombotic state, anticardiolipin antibody, emboli, vasculitis), antineuronal antibodies, immune complexes, cytokines, metabolic disorders, infection, and therapy. Diagnostic and therapeutic strategies must be individualized for both the disorder and the patient.

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