Studies were carried out on 47 bulls. Determination of polymorphism and the level of analysed indices was performed three times every three months. Statistically significant changes in the level of hematological and immunological indices caused by the growth and development of the examined animals were observed. It was also found that acid phosphatase polymorphism influenced the number of neutrophils and lymphocytes, AcP activity in leukocytes and the value of NBT reduction test.

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