Background And Objectives: Bone scintigraphy is a molecular imaging technique routinely used for the evaluation of benign and malignant bone abnormalities. This study aimed at evaluating spinal degenerative changes detected by bone scintigraphy and determining associations between image features and patients’ anthropometric and demographic variables.
Material And Method: In a cross-sectional study, 64 men and 52 women underwent bone scintigraphy. Experts identified all image regions suggesting degenerative joint disease (DJD) and classified region intensity on a 3-point scale. Image characteristics were correlated to the patients’ body mass index (BMI), age, weight, height, activity level, and sex. Data analysis included descriptive statistics and association coefficients.
Results: DJD was found in 53 patients (46%). In men, there was weak but statistically significant correlation between DJD and activity level, and DJD and age, but not BMI or weight. In women, only a weak, not statistically significant, linear correlation was found between DJD and BMI, and DJD and weight.
Conclusion: Molecular imaging with bone scintigraphy showed that spinal degenerations are associated with different anthropometric and demographic features in men and women. Interestingly, no association was found between DJD and increased body weight in men while a weak association may exist in women. The results prompt for additional studies to better determine the risk factors for DJD and low back pain in male and female patients.
Level Of Evidence: Diagnostic study, Level II (retrospective study).
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http://dx.doi.org/10.3233/BMR-140479 | DOI Listing |
Sci Rep
January 2025
Department of Nephrology, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, China.
To analyze the clinical characteristics of patients with metastatic calcification undergoing maintenance dialysis. Patients diagnosed with metastatic calcification via 99mTc-MDP bone scintigraphy between June 2019 and March 2023 at our hospital were included in this study. All patients were followed from the time of diagnosis until death, loss to follow-up, or the study endpoint (July 2023).
View Article and Find Full Text PDFRev Bras Ortop (Sao Paulo)
November 2024
Serviço de Ortopedia e Traumatologia, Hospital das Clínicas Samuel Libânio (HCSL), UNIVÁS, Pouso Alegre, MG, Brasil.
This paper described a case of talus osteonecrosis in a 13-year-old female with a diagnosis of T-type acute lymphocytic leukemia, who underwent chemotherapy and treatment with glucocorticoids, attended at the Orthopedics and Traumatology Sector of our institution. After approximately six months of treatment, the patient began to complain of sporadic pain in her left ankle with progressive worsening. Bone scintigraphy and magnetic resonance imaging of the ankles showed the presence of avascular osteonecrosis of the bilateral talar body.
View Article and Find Full Text PDFJ Echocardiogr
December 2024
Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.
Transthyretin amyloid cardiomyopathy (ATTR-CM) is becoming increasingly recognized with the aging population, advancements in understanding of disease pathobiology and the potential benefits of emerging therapies. Bone scintigraphy, including Tc-labeled pyrophosphate scintigraphy, is currently considered the first-line modality for identifying ATTR-CM. Therefore, it is important to increase the preset probability using inexpensive and simple tests including echocardiography.
View Article and Find Full Text PDFEndocrine
December 2024
Nuclear Medicine and Molecular Imaging, Institut de Cancérologie Strasbourg Europe (ICANS), University Hospitals of Strasbourg, University of Strasbourg, Strasbourg, France.
Purpose: To evaluate organ-specific response to [Lu]DOTATATE Peptide Receptor Radionuclide Therapy (PRRT) in patients with small intestine neuroendocrine tumor (SiNET) through [Ga]DOTATOC PET/CT, and to analyze tumor uptake and functional volume variations at different metastatic sites in relation to disease progression during clinical follow-up after treatment.
Methods: A retrospective analysis was conducted on 33 metastatic patients. PET/CT were performed pre-treatment (PET0), mid-treatment after two PRRT cycles (PET2), and post-treatment (PET4).
EJNMMI Rep
December 2024
Department of Oncology and Nuclear Medicine, University Hospital Centre Sestre Milosrdnice, Zagreb, Croatia.
Brown tumors or osteitis fibrosa cystica are a rare bone metabolism disorder that may mimic cancer metastasis. It represents a late manifestation of prolonged and mostly unrecognized hyperparathyroidism. In this case report we present a 44-year-old female patient with multiple lesions detected on bone scintigraphy and F- FDG-PET/CT, initially interpreted as a bone metastatic disease, rather than multiple gigantocellular bone tumors.
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