Clinical characteristics and treatment of Herlyn-Werner-Wunderlich syndrome.

Objective: To investigate the clinical characteristics and treatment of the Herlyn-Werner-Wunderlich syndrome (HWWS).

Methods: Sixty-one patients diagnosed with HWWS were retrospectively analyzed. HWWS is categorized into three types in China.

Results: Age at presentation of all the cases was after menarche. The most common clinical presentations were dysmenorrhea for type I and vaginal discharge for types II and III. Clinical presentations of types II and III may not occur until reproductive age. HWWS occurred on the right in 39/61. Excision of the obstructed vaginal septum was the treatment utilized in this cohort. After surgery, subsequent pregnancies were ipsilateral in 52.9 %.

Conclusions: Clinical presentation in untreated HWWS suggests the anatomic anomaly. Early recognition and treatment can reduce symptoms. Pregnancies occur in both the affected and unaffected uterus.