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Cureus
September 2024
Central Research Facility, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Dr. D. Y. Patil Vidyapeeth (Deemed to be University), Pune, IND.
Dr. Christian Friedrich Samuel Hahnemann (1755) was the visionary founder of homoeopathy, a system of medicine that emerged amidst the orthodox practices of his time. This biography traces Hahnemann's journey from a curious scholar in Meissen to a pivotal figure in global healthcare.
View Article and Find Full Text PDFFront Psychol
April 2024
Ningbo Innovation Center, Zhejiang University, Ningbo, China.
Background: The global dissemination of Chinese martial arts (CMAs), transcends mere physical activity; it represents a cultural and philosophical journey that contributes to enhanced psychological well-being. Capturing international attention, CMAs have engendered a network of global instructors committed to their cross-cultural teaching. However, the narrative of CMAs across the globe is incomplete without understanding the psychological factors that fuel the perseverance of these international instructors.
View Article and Find Full Text PDFUnlabelled: The mechanisms driving late relapse in uveal melanoma (UM) patients remains a medical mystery and major challenge. Clinically it is inferred that UM disseminated cancer cells (DCCs) persist asymptomatic for years-to-decades mainly in the liver before they manifest as symptomatic metastasis. Here we reveal using Gαq/11 /BAP human uveal melanoma models and human UM metastatic samples, that the neural crest lineage commitment nuclear receptor NR2F1 is a key regulator of spontaneous UM DCC dormancy in the liver.
View Article and Find Full Text PDFJ Med Biogr
February 2024
School of Medicine Dentistry and Biomedical Sciences, Queen's University Belfast, UK.
In the chronicles of medical advancement, Dr Paul Farmer stands out as a transformative figure whose unwavering commitment to healthcare equity has reshaped treatments for the disenfranchised. An American anthropologist and physician, Farmer has had a profound impact on global health which encapsulates a legacy driven by the steadfast belief that healthcare is an inalienable human right. This article explores Farmer's monumental contributions, showcasing how his dedication has revolutionized the landscape of healthcare, particularly for those marginalized and underserved.
View Article and Find Full Text PDFFront Digit Health
January 2024
Innovation & Research, Trilateral Research Ltd., Waterford, Ireland.
This paper will discuss the European funded iToBoS project, tasked by the European Commission to develop an AI diagnostic platform for the early detection of skin melanoma. The paper will outline the project, provide an overview of the data being processed, describe the impact assessment processes, and explain the AI privacy risk mitigation methods being deployed. Following this, the paper will offer a brief discussion of some of the more complex aspects: (1) the relatively low population clinical trial study cohort, which poses risks associated with data distinguishability and the masking ability of the applied anonymisation tools, (2) the project's ability to obtain informed consent from the study cohort given the complexity of the technologies, (3) the project's commitment to an open research data strategy and the additional privacy risk mitigations required to protect the multi-modal study data, and (4) the ability of the project to adequately explain the outputs of the algorithmic components to a broad range of stakeholders.
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