Acute hand ischemia after unintentional intraarterial injection of drugs: is catheter-directed thrombolysis useful?

J Vasc Interv Radiol

Departments of Radiology, University Hospitals of Geneva, Rue Gabrielle-Perret-Gentil 4, Geneva 14 1211, Switzerland.

Published: June 2014

Unintentional intraarterial injections are rare but may have devastating consequences. No consensus on treatment has been established owing to the wide variety of possible injected substances, incomplete understanding of the underlying pathophysiology, and the absence of case-controlled, prospective human studies. The aim of the present study and literature review was to evaluate the benefit of intraarterial thrombolysis combined with systemic anticoagulation therapy when an artery of the upper extremity is accidentally punctured and ischemia of the hand ensues.

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http://dx.doi.org/10.1016/j.jvir.2014.03.016DOI Listing

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