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Vaginal Dysbiosis in Infertility: A Comparative Analysis Between Women with Primary and Secondary Infertility.
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Unidad de Investigación en Salud, Hospital de Alta Especialidad Ixtapaluca, IMSS-Bienestar, Carr Federal México-Puebla Km 34.5, Ixtapaluca 56530, Mexico.
Unlabelled: Infertility, both primary and secondary, is strongly influenced by microbiological factors, with the vaginal microbiota playing a key role in reproductive health.
Objective: The aim of this study was to characterize the vaginal microbiota of 136 Mexican women diagnosed with infertility-primary (n = 58) and secondary (n = 78)-by evaluating the presence of pathogenic bacterial species and their associations with infertility conditions.
Methods: Samples were obtained through cervical swabs, and microorganism identification was performed using qPCR techniques.
Massive Sequencing of V3-V4 Hypervariable Region in Pyogenic Liver Abscesses Reveals the Presence of Unusual Bacteria Not Detected by Classical Culture Methods.
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Hospital Juárez de México, Mexico City 07760, Mexico.
Pyogenic liver abscesses (PLAs) are serious infections in which doctors often fail in identifying the causative agent due to microbiological limitations. These limitations in detecting uncommon pathogens complicate the treatment and recovery. Molecular techniques, like massive sequencing, enable the detection of uncommon pathogens and highlight the shortcomings of traditional cultures.
View Article and Find Full Text PDFCorrigendum: Modulation of local immunity by the vaginal microbiome is associated with triggering spontaneous preterm birth.
Front Immunol
January 2025
Microbiome-X, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, China.
[This corrects the article DOI: 10.3389/fimmu.2024.
View Article and Find Full Text PDFWomen with persistent/recurrent vaginal discharge should be offered multiplex-7 PCR testing.
Eur J Obstet Gynecol Reprod Biol
January 2025
Feto Maternal Centre, Al Markhiya, Doha, Qatar; Weill Cornell Medicine, Qatar; University of Leicester, UK. Electronic address:
Background: Recurrent vaginal discharge is an important cause of repeated visits to the gynaecologists. Failure to correctly identify the causative organism with standard microscopy and culture techniques results in repeated unsuccessful treatment and the risk of developing antibiotic resistance. Multiplex PCR test is increasingly being used for investigating infections where multiple organisms may be involved.
View Article and Find Full Text PDFImpact of Human Papillomavirus (HPV) on Male and Female Fertility.
Pathogens
December 2024
Department of Infectious Agents and Hygiene, University Hospital of Saint-Etienne, 42023 Saint-Etienne, France.
Human papillomaviruses (HPVs) are responsible for the majority of sexually transmitted infections (STIs), some of which are oncogenic and can cause oropharyngeal or genital cancers. The HPV prevalence at the genital level varies according to the population studied but is higher in the seminal fluid of men suffering from idiopathic infertility than in the general population. The involvement of HPV in male infertility is supported by several studies suggesting that this virus can affect sperm quality by altering sperm DNA integrity, motility, number, viability, and morphology, and by inducing the production of anti-sperm antibodies (ASAs).
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