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Population structure and ongoing microevolution of the emerging multidrug-resistant Salmonella Typhimurium ST213.
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Departamento de Microbiología Molecular, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca, MOR, Mexico.
Salmonella enterica serovar Typhimurium ST213 is an emergent multidrug-resistant sequence type associated with the food chain, and gastrointestinal and invasive infections in North America. Here, we applied genomic and phenotypic analyses to illustrate the diversity and evolution of sequence type ST213. The population structure and evolutionary history of ST213 strains, particularly the North American isolates (NA-ST213) distinguish them from other S.
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Department of Pediatrics, Sections of Hospital Medicine and Emergency Medicine, University of Colorado School of Medicine Aurora, Aurora, Colorado.
Snow White's tale in nephrology: the emerging threat of skin-whitening creams on kidney health.
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Department of Nephrology, Dialysis, Transplantation, Dr C. I. Parhon Hospital, Iasi, Romania.
The timeless tale of Snow White, with its emphasis on fair skin as a beauty ideal, mirrors a contemporary issue in nephrology: the harmful impact of skin-whitening creams on kidney health. Fairness creams have deeply embedded themselves in global society, driven by a pervasive obsession with lighter skin tones as a symbol of beauty. This widespread use reflects deeply rooted cultural beliefs and social norms, despite the significant health risks associated with these products.
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General Surgery, Hospital do Espírito Santo de Évora, Évora, PRT.
Transvaginal evisceration is a rare, potentially life-threatening condition involving herniation of intra-abdominal contents, typically the small bowel, through a defect in the vaginal wall. Most commonly observed in postmenopausal women with a history of pelvic surgery or trauma, it necessitates prompt surgical intervention. We report a unique case of transvaginal evisceration in a 67-year-old postmenopausal female with rectovaginal prolapse following minor trauma.
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Turk J Biol
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Department of Genetics and Bioengineering, Faculty of Engineering, Yeditepe University, İstanbul, Turkiye.
Article Synopsis
- MEIS1 is a key regulator in stopping cardiomyocyte cell division and is a potential target for heart-related therapies.
- Inhibition of MEIS1 through new small molecules (MEISi-1 and MEISi-2) boosts the growth and division of neonatal cardiomyocytes significantly compared to untreated cells.
- MEIS1 inhibition not only reduces the expression of certain target genes but also enhances important cardiac-specific gene expression, suggesting these inhibitors could play a vital role in heart regeneration treatments.
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