Solid adnexal masses, while less common than their cystic counterparts, may present a challenge for radiologists given the wide range of histologic entities that occur in this region. Pelvic masses, especially when large, can seem overwhelming at first but application of an algorithmic approach allows for more confident assessment. This approach focuses first on the use of anatomic relationships and interactions of various pelvic structures to localize the mass' origin. For instance, the directionality of ureteral displacement can suggest if a mass is intra or extraperitoneal. Then, key discriminating imaging features, such as the presence of fat, hypervascularity, or low T2 signal on magnetic resonance imaging (MRI) can be applied to further narrow the list of diagnostic possibilities. Entities such as leiomyomas, nerve sheath tumors, congenital uterine anomalies, and vascular abnormalities (ovarian torsion or iliac vessel aneurysm) in particular are often accurately characterized with sonography and/or MRI. For solid adnexal masses in which a definitive diagnosis by imaging is not reached, information germane to clinicians regarding further management can still be provided, principally with regard to surgical vs. nonsurgical treatment.
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http://dx.doi.org/10.1007/s00261-014-0163-4 | DOI Listing |
BMC Womens Health
December 2024
Department of Pathology, China-Japan Friendship Hospital, No. 2, Yinghuayuan East Street, Chaoyang District, Beijing, 100029, China.
Background: According to previous studies, tall cell carcinoma with reversed polarity can be easily distinguished from ductal carcinoma in situ based on the absence of myoepithelium and a typical histologic feature. However, to the best of our knowledge, no cases of papillary ductal carcinoma exhibiting tall cell and reversed polarity features with intact myoepithelium have been reported, and thus its diagnosis and prognosis remain unclear.
Case Presentation: A 54-year-old female with a palpable lump in her right breast for 3 years.
mSystems
December 2024
State Key Laboratory of Genetic Engineering, Fudan Microbiome Center, School of Life Sciences, Fudan University, Shanghai, China.
Unlabelled: Microbial metabolism of bile acids (BAs) is crucial for maintaining homeostasis in vertebrate hosts and environments. Although certain organisms involved in bile acid metabolism have been identified, a global, comprehensive elucidation of the microbes, metabolic enzymes, and bile acid remains incomplete. To bridge this gap, we employed hidden Markov models to systematically search in a large-scale and high-quality search library comprising 28,813 RefSeq multi-kingdom microbial complete genomes, enabling us to construct a secondary bile acid production gene catalog.
View Article and Find Full Text PDFJ Med Case Rep
November 2024
Surgery Department, Guelmim Military Hospital Moulay El Hassan General, Guelmim, Morocco.
Introduction: Syringocystadenocarcinoma papilliferum is an extremely rare malignant adnexal tumor that typically arises from a papilliferous syringocystadenoma (World Health Organization classification of skin tumors, 2018.). This tumor predominantly occurs in the cephalic region.
View Article and Find Full Text PDFAnn Diagn Pathol
February 2025
Department of Anatomical Pathology, Division of Pathology and Laboratory Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA. Electronic address:
Clin Nucl Med
November 2024
Department of Pathology, Aalborg University Hospital, Aalborg, Denmark.
A 67-year-old woman presented with a 12 × 20 × 24-cm adnexal tumor. Ultrasonography revealed an irregular, multilocular tumor, with increased flow in the solid components, and ascites-features that are consistent with ovarian cancer. The patient underwent 18F-FDG PET/CT and 68Ga-FAPI-46 PET/CT, both of which showed low uptake values.
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