Background: Chronic pancreatitis (CP) is a rare disease in childhood. Although ERCP is commonly performed in children, the effect of pancreatic duct stenting therapy in children with CP is unknown.
Objective: To investigate the efficacy of pancreatic duct stenting in children with CP.
Design: Retrospective analysis.
Setting: National referral center.
Patients: A total of 208 children with CP hospitalized between 1988 and 2012.
Interventions: ERCP with pancreatic duct stenting.
Main Outcome Measurements: Results of endoscopic therapy and number of pancreatitis episodes per year before and after treatment.
Results: A total of 223 pancreatic duct stenting procedures were performed in 72 children. The median number of stent replacements was 3 (range 1-21). A statistically significant decrease in the number of pancreatitis episodes per year was observed: from 1.75 to 0.23 after endoscopic treatment (P < .05). Pancreatic duct stenting was performed more frequently in patients with hereditary pancreatitis (61.5%) and in children with CP and anatomic anomalies of the pancreatic duct (65%; P < .05).
Limitations: Retrospective analysis with the assessment of adverse events based on medical history.
Conclusion: Pancreatic duct stenting therapy is a safe and effective procedure in children with CP. This therapy should be recommended especially for children with hereditary pancreatitis and patients with anatomic anomalies of the pancreatic duct.
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