Structural pathologies in the uterine cavity such as müllerian duct anomalies (MDAs) and intrauterine lesions (fibroids, polyps, synechiae) may have important roles in subinfertility, implantation failure and pregnancy outcome. Various imaging modalities such as hysterosalpingography (HSG), sonography, laparoscopy and hysteroscopy are used in the evaluation of MDAs and intrauterine lesions. Recently, three-dimensional ultrasound (3DUS) has been introduced as a non-invasive, outpatient diagnostic modality. With increased spatial awareness, it is superior to other techniques used for the same purpose.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4023499PMC

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Article Synopsis
  • Müllerian duct anomalies (MDAs) are congenital issues with the uterus caused by improperly developed Müllerian ducts, and uterus didelphys is a rare type associated with complications like infertility and pain.
  • A case study of a 21-year-old woman revealed an irregularly shaped uterus, diagnosed as a bicornuate uterus, but further examination before a scheduled surgery showed a thick vaginal septum, halting the procedure.
  • The patient ultimately underwent a cesarean section at 37 weeks, revealing two non-communicating uteri and vaginas; the study emphasizes that proper prenatal care can lead to successful pregnancy outcomes in women with this anomaly.
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Müllerian Duct Anomalies: Role in Fertility and Pregnancy.

Radiographics

October 2021

From the Department of Radiology and Biomedical Imaging, Division of Abdominal Imaging and Ultrasound (M.D.S., R.P., P.J., L.P., S.C.B., H.H.C.), Department of Radiology and Biomedical Imaging, Division of Pediatric Radiology (J.C.), Department of Obstetrics, Gynecology, and Reproductive Sciences (E.M.L.), and Department of Pathology (J.T.R.), University of California, San Francisco, 505 Parnassus Ave, 3rd Floor, M391, Box 0628, San Francisco, CA 94143.

Müllerian duct anomalies (MDAs) have important implications for the reproductive health of female patients. In patients with both infertility and recurrent pregnancy loss, the incidence of MDAs is as high as 25%. Congenital uterine anomalies are often only part of a complex set of congenital anomalies involving the cervix, vagina, and urinary tract.

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Müllerian development anomalies (MDAs) are most commonly diagnosed in the reproductive period. A bicornuate uterus is the result of a fusion defect of the Müllerian ducts, causing an abnormal fundal outline. Most of the cases are diagnosed early in life and present with obstetrical complications, such as recurrent pregnancy loss, preterm birth, intrauterine growth restriction, placental abruption, and cervical incompetence.

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Evaluation of the abdominopelvic region using MRI in patients with primary amenorrhea.

J Pediatr Endocrinol Metab

September 2019

Eskisehir Osmangazi University, Faculty of Medicine, Department of Radiology, Odunpazarı, 26480 Eskişehir, Turkey.

Background This study aimed to evaluate the imaging findings of patients who underwent an abdominal and pelvic magnetic resonance imaging (MRI) due to primary amenorrhea. Methods The pelvic and abdominal images of 34 female patients (mean age 15.61 years, range 14-19 years) were retrospectively analyzed by a single radiologist blinded to the clinical and laboratory data of the patients (other than primary amenorrhea) to evaluate the etiology of primary amenorrhea.

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Mullerian duct anomalies (MDAs) are rare, affecting approximately 1% of all women and about 3% of women with poor reproductive outcomes. These congenital anomalies usually result from one of the following categories of abnormalities of the mullerian ducts: failure of formation (no development or underdevelopment) or failure of fusion of the mullerian ducts. The American Fertility Society (AFS) classification of uterine anomalies is widely accepted and includes seven distinct categories.

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