We present the first reported case of a concomitant Leydig cell tumour (LCT) and paratesticular leiomyoma in an adult man with a history of bilateral cryptorchidism. An 80-year-old man presented with a 2-month history of a left testicular lump associated with mild discomfort and a gradual increase in size on a background of bilateral cryptorchidism requiring multiple orchidopexy procedures as a child. Ultrasound confirmed a lesion suspicious for malignancy and he proceeded to a left radical orchidectomy. Histopathological assessment of the left testis revealed a concomitant testicular LCT with rare malignant features and paratesticular leiomyoma.
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http://dx.doi.org/10.1136/bcr-2014-203682 | DOI Listing |
Cureus
December 2024
Department of Urology, Mamata Academy of Medical Sciences, Hyderabad, IND.
In this case study, we describe a 46-year-old male presenting with a palpable, gradually enlarging scrotal mass persisting over three to four years, ultimately diagnosed as paratesticular leiomyoma, who underwent enucleation of the tumor with no signs of recurrence, two years after surgery. This report underscores the significance of accurate diagnosis to avoid unnecessary treatment. We also emphasize the sequential events and findings, supported by relevant literature review, that contributed to establishing the correct diagnosis and guiding appropriate treatment decisions.
View Article and Find Full Text PDFJpn J Radiol
October 2024
Department of Radiology, National Defense Medical College, 3-2 Namiki, Tokorozawa-shi, Saitama, 359-8513, Japan.
Scrotal masses, whether cystic or solid lesions, are routinely evaluated using ultrasonography. Magnetic resonance imaging (MRI) may be used for further investigation in cases with atypical findings, difficult diagnoses, large masses, and/or unclear relationships with the surrounding tissues. Scrotal solid masses are divided into intra- and extra-testicular masses.
View Article and Find Full Text PDFJ Clin Med
February 2024
Pathology Unit, Azienda USL-IRCCS di Reggio Emilia, 42123 Reggio Emilia, Italy.
Androgen insensitivity syndrome (AIS) is a rare Mendelian disorder caused by mutations of the androgen receptor () gene on the long arm of the X chromosome. As a result of the mutation, the receptor becomes resistant to androgens, and hence, karyotypically male patients (46,XY) carry a female phenotype. Their cryptorchid gonads are prone to the development of several types of tumors (germ cell, sex cord stromal, and others).
View Article and Find Full Text PDFUrol Case Rep
March 2023
Department of Urology, Charles Nicolle Hospital, Tunis, Tunisia.
Paratesticular leiomyoma is an extremely rare benign tumour. It is often asymptomatic. It is sometimes difficult to distinguish leiomyomas from malignant testicular tumours, which leads to radical orchidectomy, despite its benign nature.
View Article and Find Full Text PDFCase Rep Oncol
February 2023
Department of Molecular Pathology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
Bilateral synchronous paratesticular leiomyoma (BSPL) is a rare tumor that originates from smooth muscle cells in the paratesticular region. Four BSPL cases have been reported sporadically, starting with the 1991 report by Aus and Boiesen. Herein, we report the case of a 60-year-old male with a bilateral scrotal mass with a maximum size of 7.
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