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User-centred design of a patient portal for persons living with home mechanical ventilation and long-term tracheostomy: a mixed methods study.
Inform Health Soc Care
January 2025
Department of Respiratory and Sleep Medicine, Austin Health, Melbourne, Australia.
Patient portals are secure online platforms that offer patients access to various functions such as personal health information. While patient portals are being increasingly offered by health services, there are limited data on their use for persons living with home mechanical ventilation (HMV) and/or long-term tracheostomy. This study, conducted at an Australian hospital's home mechanical ventilation and long-term tracheostomy services, aimed to explore the perspectives and attitudes of patients and carers regarding the introduction of a patient portal.
View Article and Find Full Text PDFHuman-Computer Interaction and Artificial Intelligence: Advancing Care Through Extended Mind Theory.
Cureus
December 2024
Psychology, University of Bath, Bath, GBR.
Artificial intelligence (AI) and mixed reality (MR), within human-computer interaction (HCI), are rapidly redefining areas of healthcare by introducing new approaches to patient care and clinical education. This editorial explores how these technologies, through Extended Mind Theory, enhance mental health treatment and medical training. AI-powered virtual therapists, using natural language processing and predictive analytics, provide accessible, personalized mental health support, allowing for remote and immersive therapy.
View Article and Find Full Text PDFDown the "Black Hole" of Sexual Violence in the Brussels Nightlife: A Qualitative Exploration of Social Media Testimonials.
Violence Against Women
January 2025
Research Center of Gender, Diversity and Intersectionality (RHEA), Vrije Universiteit Brussel (VUB), Brussels, Belgium.
The Instagram account (@Balance_ton_bar) highlighted the issue of sexual violence in Brussels nightlife sharing testimonials from victim-survivors. Set up in response to reports of drug-facilitated sexual assault at nightlife establishments, the account aimed to raise awareness and hold establishments accountable. This study examines these testimonials to explore how violence was perpetrated-through chemical drugging, alcohol use, isolation, and social power-the socio-emotional consequences for victim-survivors, and their journeys in seeking support.
View Article and Find Full Text PDFHigh-fidelity computational fluid dynamics modeling to simulate perfusion through a bone-mimicking scaffold.
Comput Biol Med
December 2024
University of Colorado Boulder, Paul M. Rady Department of Mechanical Engineering, Boulder, CO, USA; Biofrontiers Institute, University of Colorado, Boulder, CO, 80309, USA. Electronic address:
Breast cancer cells sense shear stresses in response to interstitial fluid flow in bone and induce specific biological responses. Computational fluid dynamics models have been instrumental in estimating these shear stresses to relate the cell mechanoresponse to exact mechanical signals, better informing experiment design. Most computational models greatly simplify the experimental and cell mechanical environments for ease of computation, but these simplifications may overlook complex cell-substrate mechanical interactions that significantly change shear stresses experienced by cells.
View Article and Find Full Text PDFNSUN2 lactylation drives cancer cell resistance to ferroptosis through enhancing GCLC-dependent glutathione synthesis.
Redox Biol
December 2024
China National Center for Bioinformation, Beijing, 100101, China; Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, 100101, China; University of Chinese Academy of Sciences, Beijing, 100049, China. Electronic address:
Lactate-mediated lactylation on target proteins is recently identified as the novel posttranslational modification with profound biological functions. RNA 5-methylcytosine (mC) modification possesses dynamic and reversible nature, suggesting that activity of its methyltransferase NSUN2 is actively regulated. However, how NSUN2 activity is response to acidic condition in tumor microenvironment and then regulates cancer cell survival remain to be clarified.
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