Aim: The aim of the prospective cohort study was to assess the impact of the conducted carer training on functional status improvement in patients after stroke.
Background: In recent years, the role of family in unprofessional care provision for patients in their home environment has been emphasized.
Methods: The cohort comprised 157 patients after ischemic stroke. The study group consisted of 81 patients and their carers who participated in the education program, and the control group included 76 patients. We used a repeated measures design: the patients' functional status was assessed on the day of hospital discharge and after 3 and 12 months at home.
Results: After 12 months the patients' functional status according to Barthel Index and Modified Rankin Scale significantly improved in both groups, but no difference between the groups was noted in the degree of improvement achieved.
Conclusions: The carers' participation in the education program did not significantly affect the patients' functional improvement.
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http://dx.doi.org/10.1016/j.apnr.2014.04.003 | DOI Listing |
Discov Oncol
January 2025
Medical Research Institute, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, 510080, China.
Liver hepatocellular carcinoma (LIHC) is a highly heterogeneous disease, necessitating the discovery of novel biomarkers to enhance individualized treatment approaches. Recent research has shown the significant involvement of ubiquitin-related genes (UbRGs) in the progression of LIHC. However, the prognostic value of UbRGs in LIHC has not been investigated.
View Article and Find Full Text PDFJ Am Chem Soc
January 2025
Materdicine Lab, School of Life Sciences, Shanghai University, 200444 Shanghai, P. R. China.
The presence of a substantial necrotic core in atherosclerotic plaques markedly heightens the risk of rupture, a consequence of elevated iron levels that exacerbate oxidative stress and lipid peroxidation, thereby sustaining a detrimental cycle of ferroptosis and inflammation. Concurrently targeting both ferroptosis and inflammation is crucial for the effective treatment of vulnerable plaques. In this study, we introduce gallium hexacyanoferrate nanoabsorption catalysts (GaHCF NACs) designed to disrupt this pathological cycle.
View Article and Find Full Text PDFJ Nurs Res
January 2025
Department of Medical Research, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.
Background: Population aging has led to a surge in elderly care needs worldwide. Bone aging, skeletal muscle degeneration, and osteoporosis pose critical health challenges for the elderly. The process of bone and skeletal muscle aging not only impacts the functional abilities but also increases fragility fracture risk.
View Article and Find Full Text PDFFront Cell Neurosci
January 2025
Department of Clinical Neuroscience and Rehabilitation Medicine, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Introduction: Since the onset of the COVID-19 pandemic, 775 million cases have been reported globally. While many individuals recover fully, a significant proportion develop persistent symptoms. Numerous studies have investigated the long-term symptoms of COVID-19; however, the full extent and impact of these symptoms remain inadequately understood.
View Article and Find Full Text PDFHeliyon
January 2025
Science and Technology Academic Department of Harbin Medical University Cancer Hospital, 150 Haping Road, Harbin, 150040, Heilongjiang, China.
Background: Non-small cell lung cancer (NSCLC), which accounts for about 85 % of all lung cancers, currently exhibits insensitivity to most treatment regimens. Therefore, the identification of new and effective biomarkers for NSCLC is crucial for the development of treatment strategies. Immunogenic cell death (ICD), a form of regulated cell death capable of activating adaptive immune responses and generating long-term immune memory, holds promise for enhancing anti-tumor immunity and offering promising prospects for immunotherapy strategies in NSCLC.
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