Background/aims: To compare the prevalence of positive bacterial cultures at the cesarean delivery (CD) incision site in patients with pre-operative application of chlorhexidine gluconate (CG) versus povidone iodine (PI).

Methods: Women undergoing a scheduled CD at ≥36 gestational weeks were randomly assigned to receive CG or PI. A swab of the incision site was performed at 3 min after disinfectant application and at 18 post-operative hours, and the prevalence of cultures with any detected bacterial growth was compared for the two groups.

Results: Of the 60 participants, 33 (55.0%) were in the PI group. There were no differences detected at 3 min, with 9.1% positive in the PI group versus 0% positive in the CG group (p = 0.2499). However, at 18 h, women in the PI group were seven times more likely than women in the CG group to have a positive culture (16/33 [48.5%] versus 3/27 [11.1%], OR = 7.53 [95% CI 1.67-38.83], p = 0.0023). Multivariate logistic regression demonstrated similar results: OR = 7.33 (95% CI 1.77-30.35), p = 0.0060.

Conclusion: The prevalence of positive bacterial cultures obtained at the site of the skin incision 18 h after CD was higher in the PI versus the CG group.

Download full-text PDF

Source
http://dx.doi.org/10.3109/14767058.2014.926884DOI Listing

Publication Analysis

Top Keywords

chlorhexidine gluconate
8
gluconate versus
8
versus povidone
8
povidone iodine
8
cesarean delivery
8
prevalence positive
8
positive bacterial
8
bacterial cultures
8
incision site
8
positive group
8

Similar Publications

Heterogeneity in preoperative screening and decolonization strategies among healthcare institutions.

Infect Control Hosp Epidemiol

January 2025

Division of Infectious Diseases and International Medicine, Department of Medicine, University of Minnesota Medical School, Minneapolis, MN, USA.

We surveyed 111 institutions' practices for screening and decolonization of in presurgical patients. Institutions commonly utilize universal, targeted, or no decolonization strategies. Frequently reported products were nasal mupirocin, chlorhexidine gluconate bathing, and nasal povidone-iodine.

View Article and Find Full Text PDF

Healthcare-associated infections (HAIs) significantly increase morbidity, mortality, length of hospital stays, and costs, particularly among ICU patients. Despite standard interventions, catheter-associated urinary tract infections (CAUTI) and central line-associated bloodstream infections (CLABSI) remain major HAI contributors. This study evaluated the efficacy of daily 2% chlorhexidine gluconate (CHG) bathing in reducing HAI incidence, specifically CAUTI, CLABSI, and multidrug-resistant organisms (MDROs), in a 20-bed ICU at a regional hospital.

View Article and Find Full Text PDF

Background: Native and periprosthetic joint infections are devastating conditions fraught with patient morbidity and mortality. Aseptic and septic joints are often debrided and irrigated to decrease bacterial loads when preventing or treating infection. However, the effect of clinically used irrigation solutions on the native cellular components of the synovial joint is unknown.

View Article and Find Full Text PDF

Ventriculoperitoneal (VP) shunting is frequently associated with complications of which shunt-related infections are the most common. However, controversies still exist regarding the underlying factors. This study comparing peri-operative skin preparation agents was aimed at determining which factors among previously documented determinants of shunt infection are implicated in our practice setting.

View Article and Find Full Text PDF

Background And Aim: Skin antisepsis plays a crucial role in pre-operative skin preparation, with chlorhexidine gluconate and alcohol being historically the preferred choice. However, concerns have risen regarding the development of bacterial resistance to chlorhexidine. Polyhexamethylene biguanide (PHMB) combined with Tris-ethylenediaminetetraacetic acid (Tris-EDTA) has recently emerged as a skin and wound antiseptic.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!