Fungal air spores can play a significant role in several allergic manifestations. Therefore, the identification of geographic areas of mould distribution could be helpful to the clinician, especially if associated with fungal air spore recording in homes or working environments of sensitized subjects, in determining the real clinical importance of sensitization to fungi. On this basis, we studied the occurrence of airborne fungi at two urban sites and at two rural sites in the South of Sardinia, from May 1987 to April 1988, using the gravity plate method. Our survey has pointed out a significant difference about the occurrence of airborne spores in the areas sampled. Spore concentrations were lower at the urban sites during all the survey period. On the whole 6319 fungal colonies belonging to 28 different genera have been found. Cladosporium, Alternaria, Penicillium and Aspergillus, represented by a range of species, were the most common fungi identified in all sites examined. Remarkable the incidence of Yeasts, represented by the genera Candida, Saccharomyces, Rhodotorula and Sporobolomyces. Aureobasidium, Stemphilium, Botrytis, Chaetomium, Mucor and Rhizopus have been found in all sites but they have not been steadily isolated during the survey. Several other genera have been found only sporadically. Our results seem to confirm that fungal air spores, because of its quantity and variety, can represent a serious problem for human health in Sardinia.
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Infect Prev Pract
March 2025
Central Department of Biotechnology, Tribhuvan University, Kirtipur, Nepal.
Introduction: Meticillin resistant (MRSA) is a major contributor to surgical site infections in post-operative patients. Hospital environments harbor MRSA, contributing to higher risk of nosocomial infections. Meticillin resistance is conferred by acquisition of gene, typically carried on mobile genetic element called Staphylococcal Cassette Chromosome (SCC).
View Article and Find Full Text PDFInt J Biol Macromol
January 2025
College of Ocean Food and Biological Engineering, Jimei University, Xiamen 361021, China; Fujian Provincial Key Laboratory of Food Microbiology and Enzyme Engineering, Xiamen 361021, China. Electronic address:
Urban air pollutants, mainly represented by PM containing organic and inorganic substances, can penetrate the human skin and trigger oxidative stress, potentially causing skin barrier damage and aging. κ-Carrageenan oligosaccharides as degradation products of natural sulfated polysaccharide have a great potential for skin moisturization as well as improving oxidative stress and inflammation. In this study, κ-carrageenan tetrasaccharide was obtained by enzymatic digestion of κ-carrageenan, and its role in alleviating particulate matter-induced inflammatory response in HaCaT keratinocyte cell line and skin barrier dysfunction was evaluated.
View Article and Find Full Text PDFTrop Biomed
December 2024
Department of Veterinary Paraclinical Study, Faculty of Veterinary Medicine, Universiti Malaysia Kelantan, 16100, Kota Bharu, Kelantan, Malaysia.
Bovine anaplasmosis is a tick-borne disease in cattle which is mainly caused by Anaplasma marginale and Anaplasma centrale. It poses significant economic burdens and threat on livestock industries worldwide. This study aimed to identify Anaplasma spp.
View Article and Find Full Text PDFBMC Biol
January 2025
The Jackson Laboratory for Genomic Medicine, Farmington, CT, 06032, USA.
Background: The microbiome regulates the respiratory epithelium's immunomodulatory functions. To explore how the microbiome's biodiversity affects microbe-epithelial interactions, we screened 58 phylogenetically diverse microbes for their transcriptomic effect on human primary bronchial air-liquid interface (ALI) cell cultures.
Results: We found distinct species- and strain-level differences in host innate immunity and epithelial barrier response.
Med Mycol
January 2025
Fungal Infection Working Group, International Society of Antimicrobial Chemotherapy.
Invasive mould disease (IMD) has a high mortality in immunosuppressed patients. Invasive aspergillosis (IA) is the most common IMD. A guideline for preventing IA has been published jointly by the Centers for Diseases Control and Prevention, the Infectious Disease Society of America, and the American Society of Blood and Marrow Transplantation.
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