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A study of prevalence of intestinal worm infestation and efficacy of anthelminthic drugs. | LitMetric

A study of prevalence of intestinal worm infestation and efficacy of anthelminthic drugs.

Med J Armed Forces India

Graded Specialist (Medicine), Army Hospital (R&R), New Delhi, India.

Published: April 2014

Background: Intestinal worm infestation is a global health problem. Soil-transmitted helminth (STH) infections form the most important group of intestinal worms affecting two billion people worldwide, causing considerable morbidity and suffering, though entirely preventable. The present study was undertaken to measure the parasite load in the target population and evaluate the efficacy of anthelminthic drugs.

Methods: Current study was undertaken from 01 July 2012 to 30 June 2013. All outdoor as well as indoor patients advised stool examination formed the study population and it included 2656 males and 76 females (including 6 children). Investigations included stool examination and blood counts. A single-oral dose of anthelminthic drug was given to all positive cases. Stool tests were repeated after 14-21 days to evaluate cure rate.

Results: Overall prevalence of intestinal worm infection was found to be 49.38%. Ascaris was the most common parasite (46.88%), followed by Taenia (2.1%) and Hymenolepis nana (0.21%). Cure rate was found to be 66% for Ascaris and 100% in other cases.

Conclusion: The study reveals high prevalence of intestinal helminths in our subject population and calls for immediate control measures, including preventive chemotherapy and treatment of entire 'at risk' population and improvement of their living conditions including provision of potable water.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4017176PMC
http://dx.doi.org/10.1016/j.mjafi.2013.12.009DOI Listing

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