AI Article Synopsis
- - The study investigated the impact of liver resection on the microcirculation in the liver and whether histological liver damage could be detected during surgery.
- - A total of 40 patients were divided into groups based on the extent of their liver resection, and measurements of red blood cell velocity (RBCV), sinusoidal diameter, and functional sinusoidal density were taken using sidestream dark-field (SDF) imaging.
- - The findings showed that RBCV increased after liver resection in both groups, with higher velocities linked to patients with histological damage, suggesting SDF imaging may help identify such damages during surgery.
Article Abstract
Background: In this study we aimed to evaluate effects of liver resection on hepatic microcirculation. In addition we wanted to study if histological liver damage could be detected intra-operatively.
Patients And Methods: 40 patients undergoing hepatic resection were included and grouped according to if they were operated with a major or minor resection. Hepatic microcirculation measurements were made intra-operatively before and after liver resection with sidestream dark-field (SDF) imaging. Red blood cell velocity (RBCV), sinusoidal diameter and functional sinusoidal density were determined.
Results: After hepatic resection RBCV increased in both the minor and major groups (44 μm/s, P=0.016 and 121 μm/s, P=0.002). RBCV in patients with histological damages was 225 (148-464) μm/s vs. 161 (118-329) μm/s in patients with no damage (P=0.016).
Conclusion: A hepatic resection leads to an increase of sinusoidal RBCV. SDF imaging could potentially be used to intraoperatively identify histological damages.
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| http://dx.doi.org/10.1016/j.mvr.2014.05.002 | DOI Listing |
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