A polymer-based ratiometric intracellular glucose sensor.

Chem Commun (Camb)

Center for Biosignatures Discovery Automation, Biodesign Institute, Arizona State University, Tempe 85287-6501, USA.

Published: July 2014

The glucose metabolism level reflects cell proliferative status. A polymeric glucose ratiometric sensor comprising poly(N-(2-hydroxypropyl)methacrylamide) (PHPMA) and poly[2-(methacryloyloxy)ethyl]trimethylammonium chloride (PMAETMA) was synthesized. Cellular internalization and glucose response of the polymer within HeLa cells were investigated.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4093769PMC
http://dx.doi.org/10.1039/c4cc01110dDOI Listing

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