Introduction. Observation of open-ring enhancement in magnetic resonance imaging (MRI) is considered a specificity marker for diagnosing pseudotumoral multiple sclerosis (MS). This finding is of great value in the differential diagnosis of tumefactive lesions. Case Report. We describe a 55-year-old white woman, with previous history of ovarian cancer and recent history of fatigue and bilateral retroorbital pain. Important bilateral visual impairment evolved over one month. Physical examination detected the presence of right homonymous hemianopia. Cranial MRI showed an expanding lesion with open-ring enhancement. Given the range of diagnostic possibilities, a stereotactic biopsy was performed, and histopathological examination was consistent with an active demyelinating disease. The patient was treated with 1 g of methylprednisolone and symptoms improved following a significant reduction in the lesion. Conclusions. We highlight the MRI results suggestive of pseudotumoral MS, especially open-ring enhancement, which is an important radiologic aspect to diagnosis and can assist in avoiding unnecessary biopsies.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009287 | PMC |
| http://dx.doi.org/10.1155/2014/951690 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Preparation of light-responsive polyacrylamide/carboxymethyl chitosan composite aerogel and its adsorption performance for Li.
Int J Biol Macromol
December 2024
College of Chemical Engineering and Materials Science, Tianjin University of Science and Technology, Tianjin 300457, China. Electronic address:
As an essential material for manufacturing lithium batteries, the demand of lithium is increasing, which means novel extracting method from various lithium-containing solutions is necessary. Spiropyran molecules undergo a photoisomerization reaction under light, transitioning from a closed-ring form (colorless) to an open-ring form (colored), generating multiple coordination sites to form coordination bonds with metal ions. In this paper, a polyacrylamide/carboxymethyl chitosan composite aerogel grafted with photoresponsive spiropyragroups (FeO/CNTs@PAM/CS-SP), used for extracting lithium from solutions, was prepared by dual cross-linking and vacuum freeze-drying.
View Article and Find Full Text PDFStructural insights into a DNA polymerase reading the xeno nucleic acid HNA.
Nucleic Acids Res
December 2024
Department of Chemistry, University of Konstanz, Universitätsstraße 10, 78457 Konstanz, Germany.
Xeno nucleic acids (XNAs) are unnatural analogues of the natural nucleic acids in which the canonical ribose or deoxyribose rings are replaced with alternative sugars, congener structures or even open-ring configurations. The expanding repertoire of XNAs holds significant promise for diverse applications in molecular biology as well as diagnostics and therapeutics. Key advantages of XNAs over natural nucleic acids include their enhanced biostability, superior target affinity and (in some cases) catalytic activity.
View Article and Find Full Text PDFUltrasensitive Terahertz Label-Free Metasensors Enabled by Quasi-Bound States in the Continuum.
Research (Wash D C)
September 2024
Department of Physics and International Laser Center, Lomonosov Moscow State University, Leninskie Gory 1, Moscow 19991, Russia.
Advanced sensing devices based on metasurfaces have emerged as a revolutionary platform for innovative label-free biosensors, holding promise for early diagnostics and the detection of low-concentration analytes. Here, we developed a chip-based ultrasensitive terahertz (THz) metasensor, leveraging a quasi-bound state in the continuum (BIC) to address the challenges associated with intricate operations in trace biochemical detection. The metasensor design features an open-ring resonator metasurface, which supports magnetic dipole -BIC combining functionalized gold nanoparticles (AuNPs) bound with a specific antibody.
View Article and Find Full Text PDFIsolated Tumefactive Demyelination in the Cervical Spinal Cord with Open-Ring Enhancement.
Neurol India
January 2024
Department of Radiodiagnosis, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India.
Differentiation of glioblastoma and primary central nervous system lymphomas using multiparametric diffusion and perfusion magnetic resonance imaging.
Biomed Rep
November 2023
Department of Radiology, Pham Ngoc Thach University of Medicine, Ho Chi Minh 700000, Vietnam.
The present study aimed to determine whether combining diffusion-weighted (DWI) and dynamic susceptibility contrast-enhanced perfusion-weighted (DSC-PWI) magnetic resonance imaging (MRI) could differentiate between primary central nervous system lymphoma (PCNSL) and glioblastoma (GBM). The present retrospective study evaluated 45 patients with histologically confirmed brain tumors, of which 18 had PCNSLs and 27 had GBMs. All patients underwent conventional, DWI, and DSC-PWI MRIs before the surgical removal of the lesion or stereotactic biopsy.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!