Dyes obtained from different natural sources have emerged as an important alternative to synthetic dyes. In this study, optimisation of natural colorant non-conventional extraction technique from olive waste was investigated using response surface methodology. The combined effects of extraction conditions on total phenolic content (TPC) and relative color strength (K/S) were studied using a three-level three-factor Box-Behnken design. The optimum conditions for dye extraction were found to be 0.14mol/L, 62.11min, 71.23°C and 4.5g for sodium hydroxide concentration, extraction time, temperature, and mass of the waste, respectively. The efficiency of extraction under these optimum conditions was found to be 1133.86mg/L of phenolics and relative colour strength (K/S) equal to 23.22. Further, Fourier Transform Infrared Spectroscopy was used to identify the major chemical groups in the extracted dye.
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http://dx.doi.org/10.1016/j.foodchem.2014.03.108 | DOI Listing |
Regen Biomater
December 2024
Institute of Biomedical Engineering, College of Medicine, Southwest Jiaotong University, Chengdu, Sichuan 610031, China.
Modification of polylactic acid (PLA) is a promising strategy for the next generation of bioresorbable vascular stent biomaterials. With this focus, FeMOFs nanoparticles was incorporated in PLA, and then post loading of carbon monoxide (CO) was performed by pressurization. It showed FeMOFs incorporation increased hydrophilicity of the surface and CO loading, and CO release was sustained at least for 3 days.
View Article and Find Full Text PDFTheranostics
January 2025
Institute for Innovation in Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, Massachusetts, 02129, MA.
The mannose receptor (CD206, expressed by the gene ) is a surface marker overexpressed by anti-inflammatory and pro-tumoral macrophages. As such, CD206 macrophages play key roles in the immune response to different pathophysiological conditions and represent a promising diagnostic and therapeutic target. However, methods to specifically target these cells remain challenging.
View Article and Find Full Text PDFChem Sci
December 2024
Department of Chemistry, The University of Western Ontario London Ontario N6A 5B7 Canada
Fluorophores that respond to external stimuli, such as changes in pH, have utility in bio-imaging and sensing applications. Almost all pH-responsive fluorophores rely on complex syntheses and the use of pH-responsive functional groups that are peripheral to the fluorophore framework. In this work, pH-responsive boron-containing heterocycles based on tridentate acyl pyridylhydrazone ligands were prepared.
View Article and Find Full Text PDFCurr Hematol Malig Rep
January 2025
Division of Hematology, Department of Medicine, Stanford University School of Medicine, Stanford, CA, 94305, USA.
Purpose Of Review: More than a decade following the discovery of Calreticulin (CALR) mutations as drivers of myeloproliferative neoplasms (MPN), advances in the understanding of CALR-mutant MPN continue to emerge. Here, we summarize recent advances in mehanistic understanding and in targeted therapies for CALR-mutant MPN.
Recent Findings: Structural insights revealed that the mutant CALR-MPL complex is a tetramer and the mutant CALR C-terminus is exposed on the cell surface.
Adv Mater
January 2025
Laboratory of Advanced Materials, Institute of Optoelectronics, Fudan University, Shanghai, 200438, P. R. China.
Metal single atoms (SA)-support interactions inherently exhibit significant electrochemical activity, demonstrating potential in energy catalysis. However, leveraging these interactions to modulate electronic properties and extend application fields is a formidable challenge, demanding in-depth understanding and quantitative control of atomic-scale interactions. Herein, in situ, off-axis electron holography technique is utilized to directly visualize the interactions between SAs and the graphene surface.
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