Evidence-based outcomes for mesh-based surgery for pelvic organ prolapse.

Curr Opin Urol

Department of Urology, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.

Published: July 2014

Purpose Of Review: In light of all the recent controversy regarding the use of synthetic mesh for pelvic organ prolapse, we did a retrospective review of the evidence-based outcomes and complications for its use.

Recent Findings: A total of 18 of the most recent studies in the last 5 years were selected. Studies selected were prospective randomized or quasi-randomized controlled trials that included surgical operations for pelvic organ prolapse for this review. Additionally, Cochrane review and meta-analysis of outcomes and complication were also analyzed. In terms of outcomes, the definition of successful surgery is currently being debated. Synthetic mesh provides superior anatomical and subjective cure rates compared with native tissue repair. Success rates varied greatly depending on the nature of prolapse and surgical approach. Furthermore, recurrence rates for mesh-based surgery are significantly lower than that for native tissue repair. The main unique complication of mesh is exposure and was reported in a mean of 11.4% of patients, with 6.8% of patients requiring surgical partial excision of mesh.

Summary: Mesh significantly improves anatomical outcomes with sacrocolpopexy and vaginal repair. Mesh does create the unique complication which can be reduced with training and proper patient selection. Further development of better materials is vital rather than reverting to tissue-based repair. Ultimately, the decision to use mesh should be based upon a patient's personal goals and preferences after an informed conversation with her physician.

Download full-text PDF

Source
http://dx.doi.org/10.1097/MOU.0000000000000063DOI Listing

Publication Analysis

Top Keywords

pelvic organ
12
organ prolapse
12
evidence-based outcomes
8
mesh-based surgery
8
synthetic mesh
8
native tissue
8
tissue repair
8
unique complication
8
mesh
6
outcomes mesh-based
4

Similar Publications

Application and research progress in composite stem cell materials of pelvic floor reconstruction.

Eur J Obstet Gynecol Reprod Biol

January 2025

Department of Obstetrics and Gynaecology, Key Laboratory of Birth Defects and Related Diseases of Women and Children of MOE, West China Second University Hospital, Sichuan University, Chengdu, Sichuan Province, China. Electronic address:

As an important tool for the surgical treatment of pelvic floor dysfunction, the safety of mesh must be guaranteed. Although the short-term curative effect of most synthetic mesh is satisfactory, complications often occur due to its material. Planting stem cells on mesh through specific methods may resolve the problems of mesh with poor biocompatibility or an uncontrollable rate o degradation.

View Article and Find Full Text PDF

. To develop an augmentation method that simulates cone-beam computed tomography (CBCT) related motion artifacts, which can be used to generate training-data to increase the performance of artificial intelligence models dedicated to auto-contouring tasks.The augmentation technique generates data that simulates artifacts typically present in CBCT imaging.

View Article and Find Full Text PDF

Background: The increase in survival rates among women treated for cervical cancer (CC) requires greater attention to the side effects of treatment. Although a high prevalence of pelvic floor disorders (PFD) in this population is documented, there is a lack of consensus regarding physical therapy approaches.

Methods: Cross-sectional observational study with 56 physiotherapists who answered a questionnaire.

View Article and Find Full Text PDF

Pelvic floor disorder (PFD) is a common gynecological disorder, and with the ageing of the population, PFD has a serious impact on the physical and mental health of patients and their quality of life. The most prominent of these are pelvic organ prolapse (POP) and urinary incontinence (UI), about which the etiology is still unclear, and it is urgent to explore their pathogenesis. Advances in genetics and epigenetics have provided new insights into the pathophysiology of PFD.

View Article and Find Full Text PDF

Importance: Tobacco smoking is linked to poor surgical outcomes, leading many physicians to avoid synthetic implants like mesh in smokers due to concerns about impaired healing. While long-term outcomes for smokers have been studied, the effect of smoking on 30-day postoperative complications, especially related to surgical mesh, is less understood.

Objectives: This study aimed to quantify the association between tobacco smoking and risk of postoperative infection, readmission, and reoperation within 30 days of minimally invasive apical prolapse repair.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!