School-age outcomes following a randomized controlled trial of magnesium sulfate for neuroprotection of preterm infants.

J Pediatr

Department of Neonatal Pediatrics and Intensive Care, Rouen University Hospital, Rouen, France; Region INSERM Team 28 "NeoVasc", Laboratory of Microvascular Endothelium and Neonate Brain Lesions, Institute for Biomedical Research, Rouen University, Rouen, France.

Published: August 2014

In a French randomized trial, children at school-age demonstrated no evidence of harm from fetal exposure to MgSO4 before very preterm birth. Motor dysfunction/death, qualitative behavioral disorders, cognitive difficulties, school grade repetition, and education services were decreased in the children exposed to MgSO4, although the differences were not significant.

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http://dx.doi.org/10.1016/j.jpeds.2014.04.007DOI Listing

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