The interferon-stimulating effect of immunomodulators is manifested after their combined inoculation with double-stranded NRAs (dsRNA) of natural and synthetic origin, and depends upon the time of administration of an inducer with respect to an immunomodulator and upon the dose of dsRNA. It is manifested as prolongation of interferon circulation in the bloodstream of animals up to 3 days when inosiplex is used as an immunomodulator. A still greater effect is observed when its derivative ASK is used instead of inosiplex. The interferon-stimulating effect of immunomodulators is due to cells of the immune system.
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